Anti-AF10 [HAF10 9A5/2]
Invented at Queen Mary University of London
- Datasheet
- References (2)
- Inventor Info
Info
| Catalogue Number | 151280 |
| Applications | ELISA FACS IHC IP WB |
| Antigen/Gene or Protein Targets | AF10 |
| Reactivity | Human and Mouse |
| Relevance | AF10 is a putative transcription factor containing a leucine zipper motif. A t(10;11)(p12;q23) chromosomal translocation present in a proportion of acute myeloid leukaemias results in the expression of an AF10 (carboxy-terminus)-MLL (amino-terminus) fusion protein. Clones HAF10 3A6/2, HAF10 3H10/3 and HAF10 9C6/2 are also available. |
| Host | Mouse |
| Subclass | IgG2b |
| Myeloma Used | Sp2/0-Ag14 |
| Recommended Growing Conditions | DMEM + 5% FCS |
| Strain | Balb/c |
| Research Area | Cancer, Epigenetics & Nuclear Signalling |
References: 2 entries
AF10 plays a key role in the survival of uncommitted hematopoietic cells.
Europe PMC ID: 23284727
Chamorro-Garcia et al. 2012. PLoS One. 7(12):e51626. PMID: 23284727.
WB
Add a reference
References: 2 entries
AF10 plays a key role in the survival of uncommitted hematopoietic cells.
Chamorro-Garcia et al. 2012. PLoS One. 7(12):e51626. PMID: 23284727.
WB
Add a reference
