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Anti-XRCC2 [XRCC2 7B7/3]

Invented by Dr Stephen West at Francis Crick Institute

Info

Catalogue Number 151273
Applications WB
Antigen/Gene or Protein Targets XRay Repair Cross Complementing 2 (XRCC2)
Reactivity Human
Relevance X-Ray Repair Cross Complementing 2 (XRCC2) is a RAD51 paralog. RAD51 is a eukaryotic homologue of E. coli RecA, a recombinase, and a component of the homologous recombination DNA repair pathway. RAD51 forms a nucleoprotein filament (through binding RAD52 and single stranded DNA that are exposed following double strand breaks) that initiates recombination. XRCC2 is also a component of the homologous recombination pathway.
Host Mouse
Immunogen His-tagged human XRCC2
Subclass IgG1
Positive Control HeLa nuclear extracts.
Molecular Weight (kDa) 33
Myeloma Used Sp2/0-Ag14
Recommended Growing Conditions DMEM + 5% FCS
Strain Balb/c
Notes XRCC2 7B7/3 does not recognise other paralogs.
Research Area Bacteriology, DNA Damage and Repair, Epigenetics & Nuclear Signalling

References: 3 entries

Masson et al. 2001. Genes Dev. 15(24):3296-307. PMID: 11751635.

Masson et al. 2001. Genes Dev. 15(24):3296-307. PMID: 11751635.

Cartwright et al. 1998. Nucleic Acids Res. 26(13):3084-9. PMID: 9628903.


Add a reference

References: 3 entries

Masson et al. 2001. Genes Dev. 15(24):3296-307. PMID: 11751635.

Masson et al. 2001. Genes Dev. 15(24):3296-307. PMID: 11751635.

Cartwright et al. 1998. Nucleic Acids Res. 26(13):3084-9. PMID: 9628903.


Add a reference

References: 3 entries

Masson et al. 2001. Genes Dev. 15(24):3296-307. PMID: 11751635.

Masson et al. 2001. Genes Dev. 15(24):3296-307. PMID: 11751635.

Cartwright et al. 1998. Nucleic Acids Res. 26(13):3084-9. PMID: 9628903.


Add a reference


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