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Anti-AP2g [AP2g 6E4/4]


Catalogue Number 151255
Applications IHC IP WB
Antigen/Gene or Protein Targets Activating Protein 2 (AP-2) gamma
Reactivity Human and Mouse
Relevance AP-2 is a family of developmentally regulated transcription factors which also play a role in breast cancer and melanoma. AP-2ß may be important in cardiac and kidney development. The AP-2 transcription factors form the OB2 complex that has been shown to up-regulate c-erb-B2 transcription.
Host Mouse
Immunogen Bacterially produced AP-2a/AP-2g fusion protein (c-terminal half of AP-2 gamma)
Subclass IgG1
Positive Control MCF7 cells
Molecular Weight (kDa) 50
Myeloma Used Sp2/0-Ag14
Recommended Growing Conditions E4 + 10% FCS
Strain Balb/c
Notes Antigen recovery will improve staining on paraffin sections.
Research Area Cancer, Cardiovascular, Epigenetics & Nuclear Signalling

References: 2 entries

Gee et al. 2009. J Pathol. 217(1):32-41. PMID: 18825690.

Eloranta et al. 2002. J Biol Chem. 277(34):30798-804. PMID: 12072434.

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