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|Applications||ChIP IHC WB|
|Antigen/Gene or Protein Targets||Activating Protein 2 (AP-2) alpha (Human)|
|Relevance||AP-2 is a family of developmentally regulated transcription factors which also play a role in breast cancer and melanoma. AP-2ß may be important in cardiac and kidney development. The AP-2 transcription factors form the OB2 complex that has been shown to up-regulate c-erb-B2 transcription.|
|Immunogen||Bacterialy expressed AP-2a/AP-2g fusion protein.|
|Positive Control||Extract from breast cancer cell line ZR75-1|
|Molecular Weight (kDa)||50|
|Recommended Growing Conditions||DMEM + 5% FCS|
AP2a 8G8/5 is specific for the alpha form of AP-2.
Antigen recovery using microwave or pressure cooking required for paraffin embedded tissue.
|Research Area||Cancer, Cardiovascular, Epigenetics & Nuclear Signalling|
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