Anti-DMC1 [1D12/4]
Invented by Dr Stephen West from Francis Crick Institute
Invented at Cancer Research UK London Research Institute: Clare Hall Laboratories
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Info
| Catalogue Number | 151238 |
| Applications | IHC IP WB |
| Antigen/Gene or Protein Targets | DMC1 |
| Synonyms | Disrupted meiotic cDNA 1 homolog, Disrupted meiotic cDNA 1, yeast homolog of, dJ199H16.1, DMC 1, DMC1, DMC1 dosage suppressor of mck1 homolog, DMC1 dosage suppressor of mck1 homolog meiosis specific homologous recombination (yeast), DMC1 homologue |
| Reactivity | Human |
| Relevance | DMC1 is a meiosis-specific homologue of RecA/RAD51 and is an essential component of the meiotic recombination machinery in yeast and higher eukaryotes. |
| Host | Mouse |
| Immunogen | human DMC1 protein (expressed as 6xHis fusion in E. coli) |
| Subclass | IgG1 |
| Myeloma Used | Sp2/0-Ag14 |
| Recommended Growing Conditions | DMEM + 5% FCS |
| Strain | Balb/c |
| Notes | Does not cross react with hRad51. |
| Research Area | DNA Damage and Repair, Epigenetics & Nuclear Signalling |
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