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Anti-Cdc6 [cdc6 9H8/5]

Info

Catalogue Number 151190
Applications IHC IP WB
Antigen/Gene or Protein Targets Cell-division cycle protein 6 (cdc6)
Synonyms Cell Division Cycle 6; Cdc18-Related Protein; CDC6-Related Protein; P62(Cdc6); HsCDC18; CDC18L; HsCDC6; CDC6 Cell Division Cycle 6 Homolog
Reactivity Saccharomyces cerevisiae
Relevance Cdc6 is essential for assembling the pre-replicative complex that forms at origins of DNA replication in the G1 phase of the cell cycle in budding yeast (S. cerevisiae).
Host Mouse
Immunogen cdc6 from S.Cerevisiae.
Subclass IgG1
Recommended Growing Conditions DMEM + 5% FCS
Research Area Cell Cycle, Epigenetics & Nuclear Signalling

References: 8 entries

A yeast GSK-3 kinase Mck1 promotes Cdc6 degradation to inhibit DNA re-replication.

Europe PMC ID: 23236290

Ikui et al. 2012. PLoS Genet. 8(12):e1003099. PMID: 23236290.

Zhang et al. 2007. Cancer Res. 67(8):3827-34. PMID: 17440097.

Tumor necrosis factor receptor 1/c-Jun-NH2-kinase signaling promotes human neoplasia.

Europe PMC ID: 17440097

Perkins et al. 2001. EMBO J. 20(17):4836-45. PMID: 11532947.

Separate SCF(CDC4) recognition elements target Cdc6 for proteolysis in S phase and mitosis.

Europe PMC ID: 11532947

Donovan et al. 1997. Proc Natl Acad Sci U S A. 94(11):5611-6. PMID: 9159120.

Cdc6p-dependent loading of Mcm proteins onto pre-replicative chromatin in budding yeast.

Europe PMC ID: 9159120


Add a reference

References: 8 entries

A yeast GSK-3 kinase Mck1 promotes Cdc6 degradation to inhibit DNA re-replication.

Europe PMC ID: 23236290

Ikui et al. 2012. PLoS Genet. 8(12):e1003099. PMID: 23236290.

Zhang et al. 2007. Cancer Res. 67(8):3827-34. PMID: 17440097.

Tumor necrosis factor receptor 1/c-Jun-NH2-kinase signaling promotes human neoplasia.

Europe PMC ID: 17440097

Perkins et al. 2001. EMBO J. 20(17):4836-45. PMID: 11532947.

Separate SCF(CDC4) recognition elements target Cdc6 for proteolysis in S phase and mitosis.

Europe PMC ID: 11532947

Donovan et al. 1997. Proc Natl Acad Sci U S A. 94(11):5611-6. PMID: 9159120.

Cdc6p-dependent loading of Mcm proteins onto pre-replicative chromatin in budding yeast.

Europe PMC ID: 9159120


Add a reference

References: 8 entries

A yeast GSK-3 kinase Mck1 promotes Cdc6 degradation to inhibit DNA re-replication.

Ikui et al. 2012. PLoS Genet. 8(12):e1003099. PMID: 23236290.

Zhang et al. 2007. Cancer Res. 67(8):3827-34. PMID: 17440097.

Tumor necrosis factor receptor 1/c-Jun-NH2-kinase signaling promotes human neoplasia.

Perkins et al. 2001. EMBO J. 20(17):4836-45. PMID: 11532947.

Separate SCF(CDC4) recognition elements target Cdc6 for proteolysis in S phase and mitosis.

Donovan et al. 1997. Proc Natl Acad Sci U S A. 94(11):5611-6. PMID: 9159120.

Cdc6p-dependent loading of Mcm proteins onto pre-replicative chromatin in budding yeast.


Add a reference


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