Ximbio is pleased to announce a new collaboration with The University of Manchester with the initial listing of 7 antibodies from the laboratory of Prof. Martin Humphries, Professor of Biochemistry, Vice-President and Dean in the Faculty of Life Sciences.
The University of Manchester has been nominated as part of the “golden diamond”, alongside Oxford, Imperial, UCL and Cambridge, due to its thriving research activity and reputation as one of the leading research-intensive British universities. Honoured by remarkable academic achievements and a long list of Nobel laureates, the University of Manchester continues to provide the scientific community with breakthrough discoveries and cutting-edge innovations.
Seven monoclonal antibodies from the University of Manchester will be made globally available on the Ximbio portal for researchers working on cell adhesion and signalling through integrins. These antibodies, directed against CD49e, CD49b, CD29 and CD151, have been generated in Prof. Martin Humphries’ laboratory, by a very productive team with a strong interest in understanding the role of cell adhesion molecules in orchestrating the dialogue between cells and their environment. Amongst many others, his discoveries include the description of conformational changes in integrin molecules, which define the level of connection between cells and the extracellular matrix.Through the use of mass spectrometry and biochemical analysis, Prof Humpries was able to understand the multi-component complexes of integrins, called adhesomes, and their involvement in cell movement and the different types of adhesion. Read more on the Manchester University website.
All the antibodies provided by the University of Manchester have been used in top level publications by Prof. Humphries and others, and their presence on the Ximbio website will undoubtedly promote and facilitate future research in the field of cell adhesion and signalling.
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