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Collaborative Toolkit

Collaborative Toolkit

The Collaborative Toolkit is a facility which has been created to maximise the impact of early-stage drug discovery projects via collaboration. In order to achieve this, Collaborative Toolkit will provide access to a selection of novel targeted research tools which have been developed by leading drug discovery groups in the UK. Successful research proposals will guarantee access to the novel targeted research tool as well as the expertise of the drug discovery group behind the programmes.

Phosphatidylinositol-4-phosphate 5-kinase inhibitor PIP5K Small Molecule (Collaborative Toolkit)

Invented at Cancer Research Technology – AstraZeneca Metabolism Alliance Team

Antigen/Gene or Protein Targets: Phosphatidylinositol-4-phosphate 5-kinase (PIP5K)

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Extracellular signal-related protein kinase 5 ERK5 Small Molecule (Collaborative Toolkit)

Invented by Steve Wedge at Northern Institute for Cancer Research

Antigen/Gene or Protein Targets: ERK5

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Glucose-6-phosphate Dehydrogenase inhibitor G6PD Small Molecule (Collaborative Toolkit)

Invented by Dr Ian Waddell at Cancer Research UK Manchester Institute

Antigen/Gene or Protein Targets: Glucose-6-phosphate dehydrogenase (G6PD)

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