Click on image or enlarge button to enlarge
Integrin β3/ITGB3/CD61 Antibody (F-11): sc-7311
- Integrin β3/ITGB3/CD61 Antibody (F-11) is a mouse monoclonal IgG1 κ, cited in 8 publications, provided at 200 µg/ml
- raised against a SD rat bone cell suspension
- recommended for detection of Integrin β3 of mouse and rat origin by IP, IF and FCM
- available conjugated to either phycoerythrin or FITC for IF, IHC(P) and FCM
- See Integrin β3/ITGB3/CD61 (D-11): sc-365679 for Integrin β3/ITGB3/CD61 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for Integrin β3/ITGB3/CD61 Antibody (F-11) for WB and IHC(P) applications. These reagents are now offered in bundles with Integrin β3/ITGB3/CD61 Antibody (F-11) (see ordering information below).
QUICK LINKS
SEE ALSO...
Integrins are heterodimers composed of noncovalently associated transmembrane a and b subunits. The 16 a and 8 b subunits heterodimerize to produce more than 20 different receptors. Most integrin receptors bind ligands that are components of the extracellular matrix, including Fibronectin, Collagen and Vitronectin. Certain integrins can also bind to soluble ligands such as Fibrinogen, or to counterreceptors on adjacent cells such as the intracellular adhesion molecules (ICAMs), leading to aggregation of cells. Ligands serve to cross-link or cluster integrins by binding to adjacent integrin receptors; both receptor clustering and ligand occupancy are necessary for the activation of integrin-mediated responses. In addition to mediating cell adhesion and cytoskeletal organization, integrins function as signaling receptors. Signals transduced by integrins play a role in many biological processes, including cell growth, differentiation, migration and apoptosis.