Integrin αM/CD11b Antibody (ICRF44): sc-80542
- Integrin αM/CD11b Antibody (ICRF44) is a mouse monoclonal IgG1 κ, cited in 2 publications, provided at 200 µg/ml
- raised against Integrin αM from Rheumatoid synovial cells and monocytes of human origin
- recommended for detection of Integrin αM of mouse, rat and human origin by IP, IF, IHC(P) and FCM
- See Integrin αM/CD11b (2LPM19c): sc-20050 for Integrin αM/CD11b antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for Integrin αM/CD11b Antibody (ICRF44) for IHC(P) applications. These reagents are now offered in bundles with Integrin αM/CD11b Antibody (ICRF44) (see ordering information below).
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Additional Integrin Antibodies including Integrin α 1, Integrin α 11, Integrin α 2, Integrin α 3, Integrin α 4, Integrin α 5, Integrin α 6, Integrin α 7, Integrin α 8 and Integrin α 9
Integrin αM (also designated complement component receptor-3 α, CD11b (p170), macrophage antigen a polypeptide, cell surface glycoprotein Mac-1 a subunit, MAC1A, MO1A and ITGAM) is a cell adhesion molecule that acts as a receptor for cell surface ligands such as intracellular adhesion molecules (ICAMs) or soluble ligands. Integrins are heterodimeric proteins that contain an a chain and b chain. Integrin αM combines with the Integrin β2 to form a leukocyte-specific integrin referred to as macrophage receptor 1 (Mac-1), or inactivated-C3b (iC3b) receptor 3 (CR3). Integrin αM/β2 is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.