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ICAM-1/CD54 Antibody (15.2): sc-107
- ICAM-1/CD54 Antibody (15.2) is a mouse monoclonal IgG1 κ, cited in 148 publications, provided at 200 µg/ml
- raised against an ICAM-1 positive cell preparation
- Anti-ICAM-1/CD54 Antibody (15.2) is recommended for detection of ICAM-1 of mouse, rat and human origin by WB, IP, IF, IHC(P) and FCM
- Anti-ICAM-1/CD54 Antibody (15.2) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 405 for IF, IHC(P) and FCM
- also provided azide-free for biological studies, sc-107 L, 200 µg/0.1 ml
- Contact our Technical Service Department (or your local Distributor) for more information on how to receive a FREE 10 µg sample of ICAM-1/CD54 (15.2): sc-107.
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for ICAM-1/CD54 Antibody (15.2) for WB and IHC(P) applications. These reagents are now offered in bundles with ICAM-1/CD54 Antibody (15.2) (see ordering information below).
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ICAM-1/CD54 Antibody (15.2) is an IgG1 κ mouse monoclonal ICAM-1 antibody that detects ICAM-1 of mouse, rat and human origin by WB, IP, IF, IHC(P) and FCM. ICAM-1/CD54 Antibody (15.2) is available as the non-conjugated anti-ICAM-1 antibody form, as well as multiple conjugated forms of anti-ICAM-1 antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. Cell adhesion molecules (CAMs) are a family of closely related cell surface glycoproteins involved in cell-cell interactions during growth and are thought to play important, yet separate, roles in embryogenesis and development. The intracellular adhesion molecule-1 (ICAM-1), also referred to as CD54, is an integral membrane protein of the immunoglobulin superfamily and recognizes the β2α1 and β2αM Integrins. ICAM-2 functions as a ligand for lymphocyte function-associated antigen-1 (LFA-1) and is involved in leukocyte adhesion. ICAM-3 is highly expressed on the surface of human eosinophils and, when bound to ligand, may inhibit eosinophil inflammatory responses and survival. ICAM-4, also known as LW glycoprotein, interacts with Integrins αLβ2, αMβ2, α4β1, the αV family and αIIbβ3, and selective binding to different integrins may be relevant to the pathology in a number of red blood cell associated diseases. Lastly, ICAM-5, expressed on telencephalic neurons, binds CD11a/CD18 and thus may act as an adhesion molecule for leukocyte binding in the central nervous system.
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