Anti-Cig2 antibody [CIG 3A11/5] (ab10881)
Key features and details
- Mouse monoclonal [CIG 3A11/5] to Cig2
- Suitable for: ELISA, IP
- Reacts with: Schizosaccharomyces pombe
- Isotype: IgG1
Overview
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Product name
Anti-Cig2 antibody [CIG 3A11/5] -
Description
Mouse monoclonal [CIG 3A11/5] to Cig2 -
Host species
Mouse -
Tested applications
Suitable for: ELISA, IPmore details -
Species reactivity
Reacts with: Schizosaccharomyces pombe -
Immunogen
Full length native protein (purified) corresponding to Mouse Cig2. S. pombe Cig2 purified protein (bacterial expression)
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
Storage buffer
Preservative: 0.02% Sodium azide
Constituent: 99.98% PBS -
Concentration information loading...
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Purity
Protein A purified -
Clonality
Monoclonal -
Clone number
CIG 3A11/5 -
Myeloma
Sp2 -
Isotype
IgG1 -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab10881 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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ELISA |
Use at an assay dependent concentration.
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IP |
Use at an assay dependent concentration.
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Notes |
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ELISA
Use at an assay dependent concentration. |
IP
Use at an assay dependent concentration. |
Target
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Relevance
Cig2 is a fission yeast (Schizosaccharomyces pombe) B-type S-phase cyclin and is expressed in a sharp spike peaking at G1/S period. Cig2 binds to Cdc2 (CDK), and the resulting Cdc2-Cig2 complex controls the G1/S transition of the cell cycle. -
Alternative names
- B type S phase cyclin antibody
Datasheets and documents
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SDS download
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Datasheet download
References (4)
ab10881 has been referenced in 4 publications.
- Basu S et al. Core control principles of the eukaryotic cell cycle. Nature 607:381-386 (2022). PubMed: 35676478
- Chu Z et al. A Cds1-mediated checkpoint protects the MBF activator Rep2 from ubiquitination by anaphase-promoting complex/cyclosome-Ste9 at S-phase arrest in fission yeast. Mol Cell Biol 29:4959-70 (2009). PubMed: 19596787
- Chu Z et al. Modulation of cell cycle-specific gene expressions at the onset of S phase arrest contributes to the robust DNA replication checkpoint response in fission yeast. Mol Biol Cell 18:1756-67 (2007). PubMed: 17332498
- Yamano H et al. The spike of S phase cyclin Cig2 expression at the G1-S border in fission yeast requires both APC and SCF ubiquitin ligases. Mol Cell 6:1377-87 (2000). PubMed: 11163211