B6.Cg-Dmdmdx Tg(DMD)72Thoen/LumcH
| Status | Available to order |
| EMMA ID | EM:12761 |
| International strain name | B6.Cg-Dmdmdx Tg(DMD)72Thoen/LumcH |
| Alternative name | hDMD/mdx mouse |
| Strain type | Transgenic Strains |
| Allele/Transgene symbol | human DMD gene |
| Gene/Transgene symbol | human DMD gene |
Information from provider
| Provider | Annemieke Aartsma-Rus |
| Provider affiliation | Leiden University Medical Center |
| Genetic information | Mouse model carrying the human DMD gene (hDMD) integrated in the mouse genome on an mdx background, which carries a mutation in exon 23 of the murine Dmd gene. |
| Phenotypic information | Homozygous:No overt phenotype, control mouse model for del52 hDMD/mdx mouse model.Heterozygous:No overt phenotype, control mouse model for del52 hDMD/mdx mouse model. |
| Breeding history | Mice backcrossed onto C57BL/6J for at least 8 generations. |
| References |
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| Homozygous fertile | yes |
| Homozygous viable | yes |
| Homozygous matings required | no |
| Immunocompromised | no |
Information from EMMA
| Archiving centre | Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom |
Literature references
- Generation of embryonic stem cells and mice for duchenne research.;Veltrop Marcel, van der Kaa Jos, Claassens Jill, van Vliet Laura, Verbeek Sjef, Aartsma-Rus Annemieke, ;2013;PLoS currents;5;; 24057032