B6J.Cg-Siglecftm1.2Arte/H
| Status | Available to order |
| EMMA ID | EM:12763 |
| International strain name | B6J.Cg-Siglecftm1.2Arte/H |
| Alternative name | Siglec-F KO mouse |
| Strain type | Targeted Mutant Strains : Knock-out |
| Allele/Transgene symbol | Siglecftm1.2Arte, |
| Gene/Transgene symbol | Siglecf |
Information from provider
| Provider | Paul Crocker |
| Provider affiliation | School of Life Sciences |
| Genetic information | Mouse knock-out model for the Siglecf gene. |
| Phenotypic information | Homozygous:No overt phenotype.Heterozygous:No overt phenotype. |
| Breeding history | C57BL/6 ES cells (Artemis); backcrossed to C57BL/6J for at least 8 generations. |
| References |
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| Homozygous fertile | yes |
| Homozygous viable | yes |
| Homozygous matings required | no |
| Immunocompromised | no |
Information from EMMA
| Archiving centre | Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom |
Literature references
- Siglec-F-dependent negative regulation of allergen-induced eosinophilia depends critically on the experimental model.;McMillan Sarah J, Richards Hannah E, Crocker Paul R, ;2014;Immunology letters;160;11-16; 24698729