Cat. #160671
Anti-DJ-1 [E2-1A]
Cat. #: 160671
Sub-type: Primary antibody
Unit size: 100 ug
Availability: 10-12 weeks
Target: DJ-1
Class: Monoclonal
Application: IHC ; WB
Reactivity: Human
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Yaacov Hod
Institute: Stony Brook University
Tool Details
*FOR RESEARCH USE ONLY
- Name: Anti-DJ-1 [E2-1A]
- Alternate name: PARK7
- Tool sub type: Primary antibody
- Class: Monoclonal
- Conjugation: Unconjugated
- Molecular weight: 24 kDa
- Reactivity: Human
- Host: Mouse
- Application: IHC ; WB
- Description: DJ-1 is a broadly conserved protein among both prokaryotic and eukaryotic cells. It has been identified as playing a diverse role in a range of cellular processes. DJ-1 was originally proposed to be a pro-oncogene, and has since been shown to be expressed at varying levels in breast, non-small cell lung and prostate cancer. It has been demonstrated to paly a role in the regulation of RNA-binding proteins as well as the regulation of testicular androgen receptors and fertilization. In addition, mutations in DJ-1 have been linked to autosomal recessive early-onset familial Parkinson's disease, and have been shown to be a key component of the oxidative stress and ubiquitin-proteasome system response (see Hod, 2004 PMID: 15258905 for additional details).
- Immunogen: Full length recombinant human DJ-1
- Isotype: IgM
Target Details
- Target: DJ-1
- Molecular weight: 24 kDa
- Target background: DJ-1 is a broadly conserved protein among both prokaryotic and eukaryotic cells. It has been identified as playing a diverse role in a range of cellular processes. DJ-1 was originally proposed to be a pro-oncogene, and has since been shown to be expressed at varying levels in breast, non-small cell lung and prostate cancer. It has been demonstrated to paly a role in the regulation of RNA-binding proteins as well as the regulation of testicular androgen receptors and fertilization. In addition, mutations in DJ-1 have been linked to autosomal recessive early-onset familial Parkinson's disease, and have been shown to be a key component of the oxidative stress and ubiquitin-proteasome system response (see Hod, 2004 PMID: 15258905 for additional details).
Applications
- Application: IHC ; WB
Handling
- Format: Liquid
- Unit size: 100 ug
- Shipping conditions: Shipping at 4° C
References
- Hod et al. 2004. J Cell Biochem. 92(6):1221-33. PMID: 15258905.
- Hod et al. 1999. J Cell Biochem. 72(3):435-44. PMID: 10022524.
