Cat. #160624
BCH-N-DW Neuroblastoma cell line
Cat. #: 160624
Sub-type: Primary
Unit size: 1x10^6 cells / vial
Organism: Human
Tissue: Abdomen
Disease: Cancer
Model: MYCN gene amplification present in sample
£575.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Carmel McConville
Institute: University of Birmingham
Tool Details
*FOR RESEARCH USE ONLY
- Name: BCH-N-DW Neuroblastoma cell line
- Tool sub type: Primary
- Organism: Human
- Gender: Male
- Tissue: Abdomen
- Disease: Cancer
- Growth properties: Cell lines may contain both neuronal and stromal/substrate adherent (N & S) cell types - this is a recognized characteristic of many neuroblastoma cell lines
- Model: MYCN gene amplification present in sample
- Description: Neuroblastoma is the most common extracranial solid malignancy in children. The disease possesses a broad range of clinical phenotypes with widely varying prognoses. Standard clinical and pathological assessments do not always differentiate reliably between tumor subtypes and, therefore, genetic markers are now playing an increasingly important role in treatment decisions.
- Application: Neuroblastoma cells have been used for the following: - Investigation of metabolic profiles generated by in vitro H MRS - Characterisation of genetic pathways - Discovery of epigenetically deregulated genes during neuroblastoma tumorigenesis, using genome wide DNA methylation analysis - Functional investigation of MEGF10 knockdown
- Additional notes: Karyotype data available on request STR data available on request
- Cellosaurus id: TBC
Applications
- Application: Neuroblastoma cells have been used for the following: - Investigation of metabolic profiles generated by in vitro H MRS - Characterisation of genetic pathways - Discovery of epigenetically deregulated genes during neuroblastoma tumorigenesis, using genome wide DNA methylation analysis - Functional investigation of MEGF10 knockdown
- Application notes: Tissue Site: Abdomen Patient Sex: Male MYCN gene amplification present in sample Neuroblastoma cells have been used for the following: - Investigation of metabolic profiles generated by in vitro H MRS - Characterisation of genetic pathways - Discovery of epigenetically deregulated genes during neuroblastoma tumorigenesis, using genome wide DNA methylation analysis - Functional investigation of MEGF10 knockdown Karyotype data available on request STR data available on request
Handling
- Format: Frozen
- Growth medium: Growth medium: DME/F12+15% fetal calf serum + glutamine + non-essential amino acids.
- Unit size: 1x10^6 cells / vial
- Shipping conditions: Dry ice
References
- Charlet et al. 2017. Mol Carcinog. 56(4):1290-1301. PMID: 27862318.
- Peet et al. 2007. NMR Biomed. 20(7):692-700. PMID: 17506115.
