Cat. #160436
UM-UC-1 (Human bladder transitional cell carcinoma) cell line
Cat. #: 160436
Unit size: 1x10^6 cells / vial
Organism: Human
Tissue: Lymphatic Tissue
Disease: Cancer
Model: Cancer Model
£575.00
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Contributor
Inventor: H. Grossman ; Anita Sabichi
Institute: University of Michigan
Tool Details
*FOR RESEARCH USE ONLY
- Name: UM-UC-1 (Human bladder transitional cell carcinoma) cell line
- Alternate name: UM-UC-1
- Organism: Human
- Tissue: Lymphatic Tissue
- Disease: Cancer
- Growth properties: Adherent
- Model: Cancer Model
- Description: UM-UC-1 are a human transitional cell carcinoma originating from lymphatic metastasis of transitional cell carcinoma of the bladder of a 26-year old black male. These cells were assessed for their susceptibility to adenoviral mediated gene delivery, tumor growth in nude mice and differences in genetic alterations. These assays allowed for characterization of some of the most important features in each of the respective lines in an effort to more accurately establish common observed phenomena across cells of the same type of neoplasm.Tumorigenicity studies in nude mice revealed the UM-UC-1 produced tumors, 1-1.5 cm in diameter in < 3 weeks. UM-UC-1 was more resistant to adenoviral gene transduction than several of the other cells evaluated. UM-UC-1 did, however, have one of the highest levels of Coxsackie adenovirus receptor (CAR) expression of the cells tested.
Handling
- Format: Frozen
- Growth medium: Cells were grown in Dulbecco's modified Eagle's medium (DMEM) containing 10% heat inactivated Fetal Bovine Serum (FBS) and were supplemented with 1% penicillin and streptomycin at 37?°C in 5% CO2 environment.
- Unit size: 1x10^6 cells / vial
- Shipping conditions: Dry ice
Related Tools
- Related tools: UM-UC-4 (Human adenocarcinoma lymph node metastasis) cell line ; UM-UC-3 (Human bladder transitional cell carcinoma) cell line ; UM-UC-5 (Human squamous cell carcinoma of the bladder) cell line ; UM-UC-7 (Human transitional cell carcinoma of the bladder) cell line ; UM-UC-9 (Human transitional cell carcinoma of the bladder) cell line ; UM-UC-10 (Human transitional cell carcinoma of the bladder) cell line ; UM-UC-11 (Human transitional cell carcinoma of the bladder) cell line ; UM-UC-13 (Human...
References
- Sabichi et al. 2006. J Urol. 175(3 Pt 1):1133-7. PMID: 16469639.
- Grossman et al. 1984. J Urol. 132(4):834-7. PMID: 6471236.
