Cat. #160402
Anti-1,4-dihydropyridine receptor [IIC12]
Cat. #: 160402
Unit size: 100 ug
Availability: 10-12 weeks
Target: 1,4-dihydropyridine receptor
Class: Monoclonal
Application: IP ; WB
Reactivity: Rabbit
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Institute: The University of Iowa
Tool Details
*FOR RESEARCH USE ONLY
- Name: Anti-1,4-dihydropyridine receptor [IIC12]
- Alternate name: DHPR
- Class: Monoclonal
- Conjugation: Unconjugated
- Molecular weight: 170
- Reactivity: Rabbit
- Host: Mouse
- Application: IP ; WB
- Description: 1,4-dihydropyridine receptor is present in skeletal muscle and associated with voltage-dependent calcium channels. This antibody was developed for immunoprecipitating radiolabelled dyhydropyridine receptors from digitonin solubilized triads. This antibody and it's related antibodies recognise the 170 kDa protein on nitrocellulose transfers of skeletal muscle triads, transverse tubular membreanes, and purified receptor.
- Immunogen: 0.5 mg rabbit skeletal muscle triads emulsified in Freund's complete adjuvant. After 4 weeks, immunization with 0.5 mg rabbit skeletal muscle triad in Freund's incomplete adjuvant was repeated 3-4 additional times at two week intervals. Two IP injections of GlcNAc-eluted dihydropyridine receptor were giving followed by 40 mg IV purified dihydropyridine receptor two days prior to fusion.
- Myeloma used: NS1
Target Details
- Target: 1,4-dihydropyridine receptor
- Molecular weight: 170
- Target background: 1,4-dihydropyridine receptor is present in skeletal muscle and associated with voltage-dependent calcium channels. This antibody was developed for immunoprecipitating radiolabelled dyhydropyridine receptors from digitonin solubilized triads. This antibody and it's related antibodies recognise the 170 kDa protein on nitrocellulose transfers of skeletal muscle triads, transverse tubular membreanes, and purified receptor.
Applications
- Application: IP ; WB
Handling
- Format: Liquid
- Unit size: 100 ug
- Shipping conditions: Shipping at 4° C
References
- Leung et al. 1987. J Biol Chem. 262(17):7943-6. PMID: 2439496.
