Cat. #160393
Creatine Kinase B (CK-BYK) [2E10]
Cat. #: 160393
Unit size: 100 ug
Availability: 10-12 weeks
Target: Brain-type creatine kinase
Class: Monoclonal
Application: WB ; EM ; IHC ; IF ; WB
Reactivity: Human ; Mouse ; Rat ; Rabbit
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: BÄĹ Wieringa
Institute: Radboud University Medical Centre
Tool Details
*FOR RESEARCH USE ONLY
- Name: Creatine Kinase B (CK-BYK) [2E10]
- Alternate name: CKBB, creatine phosphokinase, phosphocreatine kinase
- Class: Monoclonal
- Conjugation: Unconjugated
- Strain: Balb/c
- Reactivity: Human ; Mouse ; Rat ; Rabbit
- Host: Mouse
- Application: WB ; EM ; IHC ; IF ; WB
- Description: Creatine kinase, also known as creatine phosphokinase or phosphocreatine kinase, is an enzyme expressed by various tissues and cell types. CK catalyses the conversion of creatine and uses adenosine triphosphate to create phosphocreatine and adenosine diphosphate. Subcellular partitioning of creatine kinase contributes to the formation of patterns in intracellular ATP distribution and the fuelling of cellular processes with a high and sudden energy demand. We have previously shown that brain-type creatine kinase (CK-B) accumulates at the phagocytic cup in macrophages where it is involved in the compartmentalized generation of ATP for actin remodeling.
- Immunogen: A synthetic 17-mer peptide corresponding to a unique sequence in the amino-terminal region of human creatine kinase B
- Isotype: IgG2b
- Myeloma used: Sp2/0-Ag14
Target Details
- Target: Brain-type creatine kinase
- Target background: Creatine kinase, also known as creatine phosphokinase or phosphocreatine kinase, is an enzyme expressed by various tissues and cell types. CK catalyses the conversion of creatine and uses adenosine triphosphate to create phosphocreatine and adenosine diphosphate. Subcellular partitioning of creatine kinase contributes to the formation of patterns in intracellular ATP distribution and the fuelling of cellular processes with a high and sudden energy demand. We have previously shown that brain-type creatine kinase (CK-B) accumulates at the phagocytic cup in macrophages where it is involved in the compartmentalized generation of ATP for actin remodeling.
Applications
- Application: WB ; EM ; IHC ; IF ; WB
Handling
- Format: Liquid
- Unit size: 100 ug
- Shipping conditions: Shipping at 4° C
References
- Venter et al. 2015. Eur J Cell Biol. 94(2):114-27. PMID: 25538032.
- Sistermans et al. 1995. Cell Tissue Res. 280(2):435-46. PMID: 7781040.
- de Kok et al. 1995. Mol Cell Biochem. 143(1):59-65. PMID: 7776959.
