#158364

MZ1 small molecule (tool compound)

Cat. #158364

MZ1 small molecule (tool compound)

Cat. #: 158364

Availability: Please enquire for quantities and pricing

This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.

Contributor

Inventor: Alessio Ciulli ; Michael Zengerle ; Kwok-Ho Chan

Institute: University of Dundee

Tool Details
Handling
Target Details
References

Tool Details

*FOR RESEARCH USE ONLY

  • Tool name: MZ1 small molecule (tool compound)
  • Alternate name: BRD4, CAP, bromodomain containing 4, chromosome-associated protein, HUNK1, HUNKI, MCAP
  • Molecular formula: C49H60ClN9O8S2
  • Primary target: BRD4
  • Description: (+)-JQ1 based PROTAC that selectively degrades BRD4 in cells
  • Molecular weight: 1002.64
  • Solubility: DMSO; Ethanol

Handling

  • Purity: 1002.64 g/mol
  • Shipping conditions: Dry Ice

Target Details

  • Primary target: BRD4

References

  • Zengerle et al. 2015. ACS Chem Biol. 10(8):1770-7. PMID: 26035625.