Cat. #158323
ABQ-48 small molecule
Cat. #: 158323
Sub-type: Inhibitor
Availability: Please enquire for quantities and pricing
Application: cell hypoxia marker; fluorescence-based multiplex ELISA
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Osvaldo Cox (Retired), Beatriz Zayas
Institute: Universidad Ana G. Mendez
Tool Details
*FOR RESEARCH USE ONLY
- Tool name: ABQ-48 small molecule
- Molecular formula: C22H38CIN3
- Tool sub type: Inhibitor
- Description: Inhibitor of growth in several cancer cell line models. This small molecule can also be used as a cell hypoxia marker in 2D and 3D colon cancer cell models.
- Application: cell hypoxia marker; fluorescence-based multiplex ELISA
- Iupac: 7-benzyl-3-aminobenzimidazo[3,2-a]quinolinium chloride
- Molecular weight: 359.8514
- Solubility: 3 mM in water, 10ľM DMSO
Handling
- Purity: 359.8514 g/mol
- Shipping conditions: Dry Ice
Target Details
- Ic50: 23 uM (A431 cells), 8.6 uM (Tk6 cells), 23uM (Toledo cells)
Application Details
- Application: cell hypoxia marker; fluorescence-based multiplex ELISA
References
- VĂŠlez et al. 2017. Open Med Chem J. 11:54-65. PMID: 28761559.
- Otero et al. 2015. J Cancer Res Ther Oncol. 1:. PMID: 26086027.
