Cat. #158034
Anti-Irisin [VAB11 P2C12*C11]
Cat. #: 158034
Unit size: 100 ug
Availability: 10-12 weeks
Target: Irisin
Class: Monoclonal
Application: ELISA ; IHC ; WB
Reactivity: Human
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Abdo Alnabulsi
Institute: Vertebrate Antibodies Limited
Tool Details
*FOR RESEARCH USE ONLY
- Name: Anti-Irisin [VAB11 P2C12*C11]
- Class: Monoclonal
- Conjugation: Unconjugated
- Molecular weight: 12
- Strain: Balb/c
- Reactivity: Human
- Host: Mouse
- Application: ELISA ; IHC ; WB
- Description: Irisin belongs to the class of adipomyokines since it acts both in adipose and muscle tissue (adipokine and myokine) and is a thermogenic protein that promotes energy expenditure by white adipose tissue (WAT) browning. Irisin is secreted from muscles in response to exercise and may mediate some beneficial effects of exercise in humans, such as weight loss and thermoregulation. Irisin is a cleavage protein of fibronectin type III domain 5 (FNDC5). FNDC5 converts to irisin after exercise. Irisin dissipates energy as heat and for this reason its discovery has generated a flurry of research aimed at understanding the mechanisms of energy metabolism. Irisin is expected to be a potential therapeutic agent for the treatment of obesity and its related conditions. This tool is significant as the peptide immunogen used to generate antibodies is conserved across all vertebrates.
- Immunogen: Ovalbumin-conjugated synthetic peptide. Peptide immunogen is conserved across all vertebrates.
- Isotype: IgG
- Recommended controls: ELISA: peptide immunogen, recombinant protein WB: recombinant protein IHC: formalin-fixed, paraffin-embedded multi-tissue microarray
Target Details
- Target: Irisin
- Molecular weight: 12
- Target background: Irisin belongs to the class of adipomyokines since it acts both in adipose and muscle tissue (adipokine and myokine) and is a thermogenic protein that promotes energy expenditure by white adipose tissue (WAT) browning. Irisin is secreted from muscles in response to exercise and may mediate some beneficial effects of exercise in humans, such as weight loss and thermoregulation. Irisin is a cleavage protein of fibronectin type III domain 5 (FNDC5). FNDC5 converts to irisin after exercise. Irisin dissipates energy as heat and for this reason its discovery has generated a flurry of research aimed at understanding the mechanisms of energy metabolism. Irisin is expected to be a potential therapeutic agent for the treatment of obesity and its related conditions. This tool is significant as the peptide immunogen used to generate antibodies is conserved across all vertebrates.
Applications
- Application: ELISA ; IHC ; WB
Handling
- Format: Liquid
- Unit size: 100 ug
- Shipping conditions: Shipping at 4° C
