Anti-Golgin-97 [CDF4]

Tool Details

*FOR RESEARCH USE ONLY

• Name: Anti-Golgin-97 [CDF4]
• Alternate name: Golgin subfamily A member 1
• Class: Monoclonal
• Conjugation: Unconjugated
• Molecular weight: 88
• Reactivity: Human ; Rabbit
• Host: Mouse
• Application: IF ; WB
• Description: The Golgi complex is an intricate cytoplasmic organelle that has a major function in the processing, transporting, and sorting of intracellular proteins following synthesis in the rough endoplasmic reticulum. Golgins are Golgi-localized proteins with extensive coiled-coil structure throughout the entire polypeptide which serve as tethering molecules or matrix proteins for the cisternal architecture of Golgi apparatus. Glogins belonging to the Glutamate receptor-interacting protein (GRIP) family are targeted to the trans-face of the Golgi by their C-terminal GRIP domains and play an essential role as tethering molecules for tubulovesicular carriers of the trans-Golgi Network (TGN).Golgin-97 resides on the cytoplasmic face of the Golgi and plays an essential role as tethering molecules on the TGN for retrograde traffic from the early and/or recycling endosomes. As a GRIP family member, Golgin-97 maintains cell polarity. Binding to the Golgi membrane is mediated by the G protein family member Arl1, and this pathway is a key regulatory process for endosome–TGN traffic.
• Recommended controls: IgG1

Target Details

• Target: Golgin 97
• Molecular weight: 88
• Target background: The Golgi complex is an intricate cytoplasmic organelle that has a major function in the processing, transporting, and sorting of intracellular proteins following synthesis in the rough endoplasmic reticulum. Golgins are Golgi-localized proteins with extensive coiled-coil structure throughout the entire polypeptide which serve as tethering molecules or matrix proteins for the cisternal architecture of Golgi apparatus. Glogins belonging to the Glutamate receptor-interacting protein (GRIP) family are targeted to the trans-face of the Golgi by their C-terminal GRIP domains and play an essential role as tethering molecules for tubulovesicular carriers of the trans-Golgi Network (TGN).Golgin-97 resides on the cytoplasmic face of the Golgi and plays an essential role as tethering molecules on the TGN for retrograde traffic from the early and/or recycling endosomes. As a GRIP family member, Golgin-97 maintains cell polarity. Binding to the Golgi membrane is mediated by the G protein family member Arl1, and this pathway is a key regulatory process for endosome–TGN traffic.

Applications

• Application: IF ; WB

Handling

• Format: Liquid
• Unit size: 100 ug
• Shipping conditions: Shipping at 4° C

References

• Nozawa et al. 2009. Cell Biol Int. 33(2):148-57. PMID: 19000931.