Cat. #157782
Myrf mouse
Cat. #: 157782
Sub-type: Mouse
Availability: 6-8 weeks
Disease: Conditional ablation of Myrf gene on a defined genetic background
Model: Conditional KO
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Ben Emery
Institute: Oregon Health & Science University
Tool Details
*FOR RESEARCH USE ONLY
- Tool name: Myrf mouse
- Tool sub type: Mouse
- Disease: Conditional ablation of Myrf gene on a defined genetic background
- Model: Conditional KO
- Conditional: Yes
- Conditional description: conditional ablation of the Myrf gene
- Description: loxP flanked Myrf gene, critical for myelination of CNS.
- Genetic background: backcrossed MyrfFl/Fl mouse line in C57B/6N genetic background
- Phenotype: loxP flanked knock-in allele of Myrf
- Strain: C57BL/6
Handling
- Shipping conditions: Embryo/Spermatoza- Dry Ice
Target Details
- Target: Myrf (myelin regulatory factor)
References
- Rossetti et al. 2019. Am J Med Genet A. 179(7):1376-1382. PMID: 31069960.
- Garnai et al. 2019. PLoS Genet. 15(5):e1008130. PMID: 31048900.
- Emery et al. 2009. Cell. 138(1):172-85. PMID: 19596243.
