#156520

Anti-Myeloperoxidase (MPO) scFv (B10B) [B10BscFv]

Cat. #156520

Anti-Myeloperoxidase (MPO) scFv (B10B) [B10BscFv]

Cat. #: 156520

Sub-type: Primary antibody

Unit size: 100 ug

Availability: 10-12 weeks

Target: Myeloperoxidase

Class: Recombinant

Application: ELISA ; WB

Host: Chicken

£300.00

This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.

Contributor

Inventor: Barry McDonnell ; Caroline Murphy

Institute: Dublin City University

Tool Details
Target Details
Applications
Handling
References

Tool Details

*FOR RESEARCH USE ONLY

  • Name: Anti-Myeloperoxidase (MPO) scFv (B10B) [B10BscFv]
  • Alternate name: MPO
  • Tool sub type: Primary antibody
  • Class: Recombinant
  • Purpose: Marker
  • Conjugation: Unconjugated
  • Host: Chicken
  • Application: ELISA ; WB
  • Description: MPO is a mediator enzyme secreted by inflammatory cells e.g. activated neutrophils and monocytes. MPO produces hypochlorous acid (HOCl) from hydrogen peroxide (H2O2) and chloride anion (Cl-) (or the equivalent from a non-chlorine halide) during the neutrophil's respiratory burst, requiring heme as a cofactor. Furthermore, it oxidizes tyrosine to tyrosyl radical using hydrogen peroxide as an oxidizing agent (Heinecke et al., 1993). Both hypochlorous acid and tyrosyl radical are cytotoxic and a...
  • Immunogen: Myeloperoxidase
  • Immunogen uniprot id: TBC

Target Details

  • Target: Myeloperoxidase
  • Target background: MPO is a mediator enzyme secreted by inflammatory cells e.g. activated neutrophils and monocytes. MPO produces hypochlorous acid (HOCl) from hydrogen peroxide (H2O2) and chloride anion (Cl-) (or the equivalent from a non-chlorine halide) during the neutrophil's respiratory burst, requiring heme as a cofactor. Furthermore, it oxidizes tyrosine to tyrosyl radical using hydrogen peroxide as an oxidizing agent (Heinecke et al., 1993). Both hypochlorous acid and tyrosyl radical are cytotoxic and a...

Applications

  • Application: ELISA ; WB

Handling

  • Format: Liquid
  • Unit size: 100 ug
  • Storage buffer: 1 x PBS
  • Storage conditions: -20° C avoid repeated freeze and thaw cycles
  • Shipping conditions: Shipping at 4° C

References

  • McDonnell, Barry (2010) Development of novel antibody-based diagnostics for the early and rapid detection of cardiac markers. PhD thesis, Dublin City University.