Cat. #155101
Anti-AvW-3 [AvW-3]
Cat. #: 155101
Sub-type: Primary antibody
Unit size: 100 ug
Availability: 10-12 weeks
Target: von Willebrand Factor
Class: Monoclonal
Application: ELISA ; IP
Reactivity: Human
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Institute: Versiti Blood Research Institute
Tool Details
*FOR RESEARCH USE ONLY
- Name: Anti-AvW-3 [AvW-3]
- Alternate name: vWf
- Tool sub type: Primary antibody
- Class: Monoclonal
- Purpose: Marker
- Conjugation: Unconjugated
- Molecular weight: 250 kDa
- Reactivity: Human
- Host: Mouse
- Application: ELISA ; IP
- Description: Von Willebrand factor (vWF) is a multimeric plasma glycoprotein that functions in hemostasis as the initiator of platelet adhesion at the site of vascular injury and as the carrier of the anti-hemophilic factor, factor VIII (FVIII). Hereditary or acquired defects of VWF lead to von Willebrand disease (vWD), a bleeding diathesis of the skin and mucous membranes, causing nosebleeds, menorrhagia, and gastrointestinal bleeding.
- Immunogen: vWF (A1 domain of mature vWF)
- Myeloma used: P3X63Ag8.653
- Recommended controls: IgG1 kappa
Target Details
- Target: von Willebrand Factor
- Molecular weight: 250 kDa
- Tissue cell line specificity: Mouse
- Target background: Von Willebrand factor (vWF) is a multimeric plasma glycoprotein that functions in hemostasis as the initiator of platelet adhesion at the site of vascular injury and as the carrier of the anti-hemophilic factor, factor VIII (FVIII). Hereditary or acquired defects of VWF lead to von Willebrand disease (vWD), a bleeding diathesis of the skin and mucous membranes, causing nosebleeds, menorrhagia, and gastrointestinal bleeding.
Applications
- Application: ELISA ; IP
Handling
- Format: Liquid
- Concentration: 0.9-1.1 mg/ml
- Unit size: 100 ug
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -15° C to -25° C
- Shipping conditions: Shipping at 4° C
References
- Jacobi et al. 2012. Blood. 119(19):4543-53. PMID: 22431572.
- Zhao et al. 2007. J Thromb Haemost. 5(9):1963-70. PMID: 17723136.
- Rosenberg et al. 2002. Blood. 100(5):1699-706. PMID: 12176890.
- Nakayama et al. 2002. J Biol Chem. 277(24):22063-72. PMID: 11943773.
- Hillery et al. 1998. Blood. 91(5):1572-81. PMID: 9473222.
- Mancuso et al. 1996. Blood. 88(7):2559-68. PMID: 8839848.
- Scott et al. 1991. Am J Clin Pathol. 96(6):723-8. PMID: 1746488.
- Kawai et al. 1987. Ann N Y Acad Sci. 509:60-...
