#155096

Anti-GpIb (CD42) [MBC 142.1]

Cat. #155096

Anti-GpIb (CD42) [MBC 142.1]

Cat. #: 155096

Unit size: 100 ug

Availability: 10-12 weeks

Target: Glycoprotein 1B

Class: Monoclonal

Application: ELISA ; ELISA ; IP ; WB

Reactivity: Human

Host: Mouse

£300.00

This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.

Contributor

Institute: Versiti Blood Research Institute

Tool Details
Target Details
Applications
Handling
References

Tool Details

*FOR RESEARCH USE ONLY

  • Name: Anti-GpIb (CD42) [MBC 142.1]
  • Alternate name: GPIb
  • Class: Monoclonal
  • Conjugation: Unconjugated
  • Molecular weight: 145
  • Reactivity: Human
  • Host: Mouse
  • Application: ELISA ; ELISA ; IP ; WB
  • Description: GPIb is a platelet glycoprotein and a receptor for von Willebrand factor. Consists of alpha and beta subunits. Forms a multiprotein complex with GPIX and GPV. Binding of VWF to this complex initiates platelet adhesion to the sub-endothelium after vascular injury. Binding of AP-1 to GP1b alpha inhibits binding of VWF to GP1b alpha.
  • Immunogen: gpIb
  • Myeloma used: P3X63Ag8.653
  • Recommended controls: IgG1

Target Details

  • Target: Glycoprotein 1B
  • Molecular weight: 145
  • Target background: GPIb is a platelet glycoprotein and a receptor for von Willebrand factor. Consists of alpha and beta subunits. Forms a multiprotein complex with GPIX and GPV. Binding of VWF to this complex initiates platelet adhesion to the sub-endothelium after vascular injury. Binding of AP-1 to GP1b alpha inhibits binding of VWF to GP1b alpha.

Applications

  • Application: ELISA ; ELISA ; IP ; WB

Handling

  • Format: Liquid
  • Concentration: 0.9-1.1mg/ml
  • Unit size: 100 ug
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -15° C to -25° C
  • Shipping conditions: Shipping at 4° C

References

  • Bougie et al. 2001. Blood. 97(12):3846-50. PMID: 11389025.