#155090

Anti-AvW-1 (von Willebrand Factor) [A8-1]

Cat. #155090

Anti-AvW-1 (von Willebrand Factor) [A8-1]

Cat. #: 155090

Sub-type: Primary antibody

Unit size: 100 ug

Availability: 10-12 weeks

Target: von Willebrand Factor

Class: Monoclonal

Application: ELISA ; IF ; IP ; WB

Reactivity: Human

Host: Mouse

£300.00

This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.

Contributor

Institute: Versiti Blood Research Institute

Tool Details
Target Details
Applications
Handling
References

Tool Details

*FOR RESEARCH USE ONLY

  • Name: Anti-AvW-1 (von Willebrand Factor) [A8-1]
  • Alternate name: vWf
  • Tool sub type: Primary antibody
  • Class: Monoclonal
  • Purpose: Marker
  • Conjugation: Unconjugated
  • Molecular weight: 250 kDa
  • Reactivity: Human
  • Host: Mouse
  • Application: ELISA ; IF ; IP ; WB
  • Description: von Willebrand factor (vWF) is a multimeric glycoprotein that functions in hemostasis as the initiator of platelet adhesion at the site of vascular injury and as the carrier of the anti-hemophilic factor, factor VIII (FVIII). Hereditary or acquired defects of VWF lead to von Willebrand disease (vWD), a bleeding diathesis of the skin and mucous membranes, causing nosebleeds, menorrhagia, and gastrointestinal bleeding.
  • Immunogen: vWF (COOH terminus of mature vWF)
  • Myeloma used: P3X63Ag8.653
  • Recommended controls: IgG2a

Target Details

  • Target: von Willebrand Factor
  • Molecular weight: 250 kDa
  • Tissue cell line specificity: Mouse
  • Target background: von Willebrand factor (vWF) is a multimeric glycoprotein that functions in hemostasis as the initiator of platelet adhesion at the site of vascular injury and as the carrier of the anti-hemophilic factor, factor VIII (FVIII). Hereditary or acquired defects of VWF lead to von Willebrand disease (vWD), a bleeding diathesis of the skin and mucous membranes, causing nosebleeds, menorrhagia, and gastrointestinal bleeding.

Applications

  • Application: ELISA ; IF ; IP ; WB

Handling

  • Format: Liquid
  • Concentration: 0.9-1.1 mg/ml
  • Unit size: 100 ug
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -15° C to -25° C
  • Shipping conditions: Shipping at 4° C

References

  • Flood et al. 2018. Res Pract Thromb Haemost. 2(2):390-398. PMID: 30046743.
  • Haberichter et al. 2008. Blood. 111(10):4979-85. PMID: 18344424.
  • Rosenberg et al. 2002. Blood. 100(5):1699-706. PMID: 12176890.
  • Hillery et al. 1998. Blood. 91(5):1572-81. PMID: 9473222.
  • Rosenberg et al. 1998. J Clin Invest. 101(3):613-24. PMID: 9449695.
  • Scott et al. 1991. Am J Clin Pathol. 96(6):723-8. PMID: 1746488.
  • Kroner et al. 1991. J Biol Chem. 266(29):19146-9. PMID: 1918030.
  • Montgomery et al. 1986. ...