Cat. #154843
Anti-XRCC2 [XRCC2 7B7/3] rAb
Cat. #: 154843
Sub-type: Primary antibody
Unit size: 100 ug
Availability: 10-12 weeks
Target: XRay Repair Cross Complementing 2 (XRCC2)
Class: Recombinant
Reactivity: Human
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Madalena Tarsounas ; Stephen West
Institute: Absolute Antibody; Cancer Research UK, London Research Institute: Clare Hall Laboratories
Tool Details
*FOR RESEARCH USE ONLY
- Name: Anti-XRCC2 [XRCC2 7B7/3] rAb
- Clone: XRCC2 7B7/3
- Tool sub type: Primary antibody
- Class: Recombinant
- Conjugation: Unconjugated
- Molecular weight: 33 kDa
- Reactivity: Human
- Host: Mouse
- Description: X-Ray Repair Cross Complementing 2 (XRCC2) is a RAD51 paralog. RAD51 is a eukaryotic homologue of E. coli RecA, a recombinase, and a component of the homologous recombination DNA repair pathway. RAD51 forms a nucleoprotein filament (through binding RAD52 and single stranded DNA that are exposed following double strand breaks) that initiates recombination. XRCC2 is also a component of the homologous recombination pathway.
- Immunogen: His-tagged human XRCC2
- Isotype: IgG1
- Recommended controls: HeLa nuclear extracts.
Target Details
- Target: XRay Repair Cross Complementing 2 (XRCC2)
- Molecular weight: 33 kDa
- Tissue cell line specificity: HeLa nuclear extracts.
- Target background: X-Ray Repair Cross Complementing 2 (XRCC2) is a RAD51 paralog. RAD51 is a eukaryotic homologue of E. coli RecA, a recombinase, and a component of the homologous recombination DNA repair pathway. RAD51 forms a nucleoprotein filament (through binding RAD52 and single stranded DNA that are exposed following double strand breaks) that initiates recombination. XRCC2 is also a component of the homologous recombination pathway.
Handling
- Format: Liquid
- Unit size: 100 ug
- Shipping conditions: Shipping at 4° C
References
- Cartwright et al. 1998. Nucleic Acids Res. 26(13):3084-9. PMID: 9628903.
- Identification and purification of two distinct complexes containing the five RAD51 paralogs.
- Masson et al. 2001. Genes Dev. 15(24):3296-307. PMID: 11751635.
- Masson et al. 2001. Genes Dev. 15(24):3296-307. PMID: 11751635.
- The XRCC2 DNA repair gene from human and mouse encodes a novel member of the recA/RAD51 family.
