Cat. #154827
Anti-Integrin b3 [Y2/51] rAb
Cat. #: 154827
Sub-type: Primary antibody
Unit size: 100 ug
Availability: 10-12 weeks
Target: Integrin ?3 (CD61; GPIIIa)
Class: Recombinant
Reactivity: Human
Host: Mouse
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Institute: Absolute Antibody ; University of Oxford
Tool Details
*FOR RESEARCH USE ONLY
- Name: Anti-Integrin b3 [Y2/51] rAb
- Alternate name: Integrin Subunit Beta; Integrin; Beta 3 (Platelet Glycoprotein IIIa; Antigen CD61); Platelet Membrane Glycoprotein IIIa; Antigen CD61; GPIIIa; GP3A; Platelet Glycoprotein IIIa; Integrin Beta 3; CD61 Antigen; BDPLT16; BDPLT2; CD61; GT
- Clone: Y2/51
- Tool sub type: Primary antibody
- Class: Recombinant
- Conjugation: Unconjugated
- Reactivity: Human
- Host: Mouse
- Description: Recombinant antibody which can detect CD61 marker on megakaryocytes.
- Immunogen: Phytohaemagglutin-stimulated peripheral blood cells
- Immunogen uniprot id: P05106
- Isotype: IgG1
Target Details
- Target: Integrin ?3 (CD61; GPIIIa)
- Target background: Integrins are heterodimeric cell surface receptors composed of alpha and beta subunits, which mediate cell-cell and cell-extracellular matrix attachments. Changes in integrin expression have been shown to be important for the growth and early metastatic capacity of melanoma cells and aberrant integrin expression has been found in many epithelial tumours. CD61/ integrin b3 is a glycoprotein found on megakaryocytes, osteoclasts, platelets and their precursors. CD61 antigen plays a role in plate...
Handling
- Format: Liquid
- Concentration: 1 mg/ml
- Unit size: 100 ug
- Storage conditions: Store at -20° C frozen. Avoid repeated freeze / thaw cycles
- Shipping conditions: Shipping at 4° C
Related Tools
- Related tools: Anti-Integrin b3 [Y2/51]
References
- Brune et al. 2007. Eur Cell Mater. 14:78-90
- Complex formation of platelet membrane glycoproteins IIb and IIIa with fibrinogen.
- discussion 90-1. PMID: 18085506.
- Gatter et al. 1988. Histopathology. 13(3):257-67. PMID: 3192191.
- Immunological study of in vitro maturation of human megakaryocytes.
- In vitro comparison of human fibroblasts from intact and ruptured ACL for use in tissue engineering.
- Nachman et al. 1982. J Clin Invest. 69(2):263-9. PMID: 6460044.
- The immunohistological de...
