Cat. #154821
Anti-DMC1 [2H12/4] rAb
Cat. #: 154821
Sub-type: Primary antibody
Unit size: 100 ug
Availability: 10-12 weeks
Target: DMC1
Class: Recombinant
Reactivity: Bovine ; Human ; Mouse
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Institute: Absolute Antibody; Cancer Research UK, London Research Institute: Clare Hall Laboratories
Tool Details
*FOR RESEARCH USE ONLY
- Name: Anti-DMC1 [2H12/4] rAb
- Alternate name: Disrupted meiotic cDNA 1 homolog, Disrupted meiotic cDNA 1, yeast homolog of, dJ199H16.1, DMC 1, DMC1, DMC1 dosage suppressor of mck1 homolog, DMC1 dosage suppressor of mck1 homolog meiosis specific homologous recombination (yeast), DMC1 homologue
- Clone: 2H12/4
- Tool sub type: Primary antibody
- Class: Recombinant
- Conjugation: Unconjugated
- Reactivity: Bovine ; Human ; Mouse
- Host: Mouse
- Description: DMC1 is a meiosis-specific homologue of RecA/RAD51 and is an essential component of the meiotic recombination machinery in yeast and higher eukaryotes.
- Immunogen: human DMC1 protein (expressed as 6xHis fusion in E. coli and band cut out of gel of insoluble pelet)
- Isotype: IgG2a
Target Details
- Target: DMC1
- Target background: DMC1 is a meiosis-specific homologue of RecA/RAD51 and is an essential component of the meiotic recombination machinery in yeast and higher eukaryotes.
Handling
- Format: Liquid
- Unit size: 100 ug
- Shipping conditions: Shipping at 4° C
References
- Erenpreisa et al. 2009. Exp Cell Res. 315(15):2593-603. PMID: 19463812.
- Ikbkap/Elp1 deficiency causes male infertility by disrupting meiotic progression.
- Lin et al. 2013. PLoS Genet. 9(5):e1003516. PMID: 23717213.
- Masson et al. 1999. EMBO J. 18(22):6552-60. PMID: 10562567.
- The meiosis-specific recombinase hDmc1 forms ring structures and interacts with hRad51.
- The role of meiotic cohesin REC8 in chromosome segregation in gamma irradiation-induced endopolyploid tumour cells.
