#154780

Anti-DGKa [M8]

Cat. #154780

Anti-DGKa [M8]

Cat. #: 154780

Sub-type: Primary antibody

Unit size: 100 ug

Availability: 10-12 weeks

Target: DGKa

Class: Monoclonal

Application: IP ; WB

Reactivity: Human

Host: Mouse

£300.00

This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.

Contributor

Institute: Netherlands Cancer Institute

Tool Details
Target Details
Applications
Handling
References

Tool Details

*FOR RESEARCH USE ONLY

  • Name: Anti-DGKa [M8]
  • Alternate name: DGKA; Diacylglycerol Kinase Alpha
  • Tool sub type: Primary antibody
  • Class: Monoclonal
  • Conjugation: Unconjugated
  • Molecular weight: 77 kDa
  • Strain: Balb/c
  • Reactivity: Human
  • Host: Mouse
  • Application: IP ; WB
  • Description: Diacylglycerol kinase alpha is an enzyme that belongs to the eukaryotic diacylglycerol kinase family. It acts as a modulator that competes with protein kinase C for the second messenger diacylglycerol in intracellular signalling pathways. It also plays an important role in the resynthesise of phosphatidylinositol's and phosphorylating diacylglycerol to phosphatidic acid.
  • Immunogen: Immunized with an Escherichia coli cell-expressed, affinity-purified glutathione S-transferase protein of a C-terminal portion (part of the Catalytic domain) of Rat DGKu.
  • Isotype: IgG1
  • Myeloma used: Sp2/0-Ag14

Target Details

  • Target: DGKa
  • Molecular weight: 77 kDa
  • Target background: Diacylglycerol kinase alpha is an enzyme that belongs to the eukaryotic diacylglycerol kinase family. It acts as a modulator that competes with protein kinase C for the second messenger diacylglycerol in intracellular signalling pathways. It also plays an important role in the resynthesise of phosphatidylinositol's and phosphorylating diacylglycerol to phosphatidic acid.

Applications

  • Application: IP ; WB

Handling

  • Format: Liquid
  • Concentration: 0.9-1.1 mg/ml
  • Unit size: 100 ug
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -15° C to -25° C
  • Shipping conditions: Shipping at 4° C

References

  • Cutrupi et al. 2000. EMBO J. 19(17):4614-22. PMID: 10970854.
  • Schaap et al. 1993. Biochem J. 289 ( Pt 3):875-81. PMID: 7679574.