Cat. #154750
Anti-TCR gamma delta [11F2] monoclonal antibody
Cat. #: 154750
Sub-type: Primary antibody
Unit size: 100 ug
Availability: 3-4 weeks
Target: TCR yd
Class: Monoclonal
Application: ELISA ; FACS ; IHC ; IP
Reactivity: Human
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Institute: Netherlands Cancer Institute
Tool Details
*FOR RESEARCH USE ONLY
- Name: Anti-TCR gamma delta [11F2] monoclonal antibody
- Tool sub type: Primary antibody
- Class: Monoclonal
- Conjugation: Unconjugated
- Strain: Balb/c
- Reactivity: Human
- Host: Mouse
- Application: ELISA ; FACS ; IHC ; IP
- Description: This monoclonal antibody recognises the gamma delta T cell receptor (gamma delta TCR). This antibody can be used to detect populations of gamma delta T cells. This antibody reacts with human gamma delta TCR in native as well as denatured states.
- Immunogen: Purified native TCRg/d
- Isotype: IgG1
- Myeloma used: Sp2/0-Ag14
Target Details
- Target: TCR yd
- Target background: The T-cell receptor (TCR) is a molecule found on the surface of T cells, or T lymphocytes, that is responsible for recognising fragments of antigen as peptides bound to major histocompatibility complex (MHC) molecules. The TCR is composed of two different protein chains. In humans, in 95% of T cells the TCR consists of an alpha chain and a beta chain, whereas in 5% of T cells the TCR consists of gamma and delta (y/d) chains. This ratio changes during ontogeny and in diseased states such as leukaemia, as well as autoimmune diseases like psoriasis.
Applications
- Application: ELISA ; FACS ; IHC ; IP
Handling
- Format: Liquid
- Concentration: 0.9-1.1 mg/ml
- Unit size: 100 ug
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -15° C to -25° C
- Shipping conditions: Shipping at 4° C
References
- Vroom et al. 1991. J Clin Pathol. 44(12):1012-7. PMID: 1838746.
- Bos et al. 1990. J Invest Dermatol. 94(1):37-42. PMID: 1688597.
- Borst et al. 1988. J Exp Med. 167(5):1625-44. PMID: 2966845.
