#154333

pCMV-Tag/M1 S245X vector

Cat. #154333

pCMV-Tag/M1 S245X vector

Cat. #: 154333

Sub-type: pCMV-Tag

Availability: Please enquire for quantities and pricing

Target: spastin

Bacterial Resistance: Kanamycin

This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.

Contributor

Institute: Drexel University

Tool Details
Target Details
References

Tool Details

*FOR RESEARCH USE ONLY

  • Tool name: pCMV-Tag/M1 S245X vector
  • Tool sub type: pCMV-Tag
  • Backbone size without insert: 4300
  • Bacterial resistance: Kanamycin
  • Description: Plasmids for the study of hereditary spastic paraplegia
  • Additional notes: Plasmids for the study of hereditary spastic paraplegia

Target Details

  • Target: spastin

References

  • Solowska et al. 2017. Mol Biol Cell. 28(13):1728-1737. PMID: 28495799.
  • Truncating mutations of SPAST associated with hereditary spastic paraplegia indicate greater accumulation and toxicity of the M1 isoform of spastin.