#154230

HtrA3 (Clone 2C4)

Cat. #154230

HtrA3 (Clone 2C4)

Cat. #: 154230

Sub-type: Primary antibody

Unit size: 100 ug

Availability: 10-12 weeks

Target: Human HtrA3 (high temperature requirement factor A)

Class: Monoclonal

Application: WB

Reactivity: Human

Host: Mouse

£300.00

This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.

Contributor

Institute: Hudson Institute Of Medical Research

Tool Details
Target Details
Applications
Handling
Related Tools
References

Tool Details

*FOR RESEARCH USE ONLY

  • Name: HtrA3 (Clone 2C4)
  • Alternate name: HtrA3
  • Tool sub type: Primary antibody
  • Class: Monoclonal
  • Conjugation: Unconjugated
  • Molecular weight: 48 kDa (46.9 kDa plus 1 kDa for the His tag)
  • Strain: Balb/c
  • Reactivity: Human
  • Host: Mouse
  • Application: WB
  • Description: Potential marker for preeclampsia. Detection of endogenous HtrA3 proteins in human serum HtrA3 are oligomeric serine proteases involved in protein quality control , regulate signal transduction in cell growth, apoptosis, inflammation in cancer, arthritis, neurodegenerative and neuromuscuclar disorders, age-related macular degeneration, pregnancy-specific disease preecampsia
  • Immunogen: synthetic peptide TIKIHPKKKL (corresponding to residues 230-239 in both HtrA3-L and HtrA3-S
  • Immunogen uniprot id: P83110, HTRA3_HUMAN
  • Myeloma used: Sp2/0-Ag14

Target Details

  • Target: Human HtrA3 (high temperature requirement factor A)
  • Molecular weight: 48 kDa (46.9 kDa plus 1 kDa for the His tag)
  • Target background: Potential marker for preeclampsia. Detection of endogenous HtrA3 proteins in human serum HtrA3 are oligomeric serine proteases involved in protein quality control , regulate signal transduction in cell growth, apoptosis, inflammation in cancer, arthritis, neurodegenerative and neuromuscuclar disorders, age-related macular degeneration, pregnancy-specific disease preecampsia

Applications

  • Application: WB

Handling

  • Format: Liquid
  • Unit size: 100 ug
  • Shipping conditions: Shipping at 4° C

Related Tools

  • Related tools: HtrA3 Monoclonal Antibody (Clone 6G6) ; HtrA3 Monoclonal Antibody (Clone 9C9) ; HtrA3 Monoclonal Antibody (Clone 3E6) ; HtrA3 Monoclonal Antibody (Clone 10H10)

References

  • 25248123
  • 27932697
  • HtrA3 as an early marker for preeclampsia: specific monoclonal antibodies and sensitive high-throughput assays for serum screening.
  • Dynon et al. 2012. PLoS One. 7(9):e45956. PMID: 23049902.