#154228

PC6 (Clone 8F5)

Cat. #154228

PC6 (Clone 8F5)

Cat. #: 154228

Unit size: 100 ug

Availability: 10-12 weeks

Target: Proprotein convertase 5/6A (PC6)

Class: Monoclonal

Application: IHC ; WB

Reactivity: Human

Host: Mouse

£300.00

This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.

Contributor

Institute: Hudson Institute of Medical Research

Tool Details
Target Details
Applications
Handling
Related Tools
References

Tool Details

*FOR RESEARCH USE ONLY

  • Name: PC6 (Clone 8F5)
  • Alternate name: PC6
  • Class: Monoclonal
  • Conjugation: Unconjugated
  • Molecular weight: 90
  • Strain: Balb/c
  • Reactivity: Human
  • Host: Mouse
  • Application: IHC ; WB
  • Description: Potential uterine fluid biomarker for endometrium receptivity. Determining endometrial receptivity is vital in in vitro fertilization (IVF) treatment because the timing of embryo transfer needs to be synchronized with endometrial receptivity. We have previously demonstrated that proprotein convertase 5/6A (PC6) is highly expressed in the receptive endometrium and that PC6 is critical for receptivity establishment in women. Endometrial PC6 is secreted into the uterine fluid, and levels correla...
  • Immunogen: Synthetic peptides of human PC6 (PSGYLLDLGMC 857-867 aa; CPPGHYHADK 674-684 aa; NSAVRSIYKASGC 482-494 aa conjugated to keyhole limpet hemocyanin though a C-terminal Cys
  • Myeloma used: Sp2/0-Ag14

Target Details

  • Target: Proprotein convertase 5/6A (PC6)
  • Molecular weight: 90
  • Target background: Potential uterine fluid biomarker for endometrium receptivity. Determining endometrial receptivity is vital in in vitro fertilization (IVF) treatment because the timing of embryo transfer needs to be synchronized with endometrial receptivity. We have previously demonstrated that proprotein convertase 5/6A (PC6) is highly expressed in the receptive endometrium and that PC6 is critical for receptivity establishment in women. Endometrial PC6 is secreted into the uterine fluid, and levels correla...

Applications

  • Application: IHC ; WB

Handling

  • Format: Liquid
  • Unit size: 100 ug
  • Shipping conditions: Shipping at 4° C

Related Tools

  • Related tools: PC6 Monoclonal Antibody (Clone 9H12)

References

  • Heng et al. 2015. Anal Biochem. 475:14-21. PMID: 25554488.
  • Development of a high-throughput assay for human proprotein convertase 5/6 for detecting uterine receptivity.