#153906

Anti-O-linked N-acetylglucosamine (O-GlcNAc) [8C3.H2]

Cat. #153906

Anti-O-linked N-acetylglucosamine (O-GlcNAc) [8C3.H2]

Cat. #: 153906

Sub-type: Primary antibody

Unit size: 100 ug

Availability: 10-12 weeks

Target: O-linked N-acetylglucosamine

Class: Monoclonal

Application: ELISA ; WB

Reactivity: Mammals

Host: Mouse

£300.00

This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.

Contributor

Inventor: Lance Wells

Institute: University of Georgia

Tool Details
Target Details
Applications
Handling
References

Tool Details

*FOR RESEARCH USE ONLY

  • Name: Anti-O-linked N-acetylglucosamine (O-GlcNAc) [8C3.H2]
  • Alternate name: O-GlcNAc
  • Tool sub type: Primary antibody
  • Class: Monoclonal
  • Conjugation: Unconjugated
  • Reactivity: Mammals
  • Host: Mouse
  • Application: ELISA ; WB
  • Description: The study of O-GlcNAc, a ubiquitous translation and transcription regulator which is found in a wide variety of proteins, is of great relevance to multiple chronic human and veterinary diseases. These include diabetes (and its effects in the heart, kidneys and eyes), cardiovascular disease, neurodegenerative disorders involving both plaque and tangle formation, inflammatory processes, liver disease, fibrosis, metabolic disorders and cancer. There is fast growing collection of evidence that O-GlcNAcylation plays a pivotal role in epigenetics.
  • Immunogen: Synthetic peptide O-GlcNAc
  • Isotype: IgG3

Target Details

  • Target: O-linked N-acetylglucosamine
  • Target background: The study of O-GlcNAc, a ubiquitous translation and transcription regulator which is found in a wide variety of proteins, is of great relevance to multiple chronic human and veterinary diseases. These include diabetes (and its effects in the heart, kidneys and eyes), cardiovascular disease, neurodegenerative disorders involving both plaque and tangle formation, inflammatory processes, liver disease, fibrosis, metabolic disorders and cancer. There is fast growing collection of evidence that O-GlcNAcylation plays a pivotal role in epigenetics.

Applications

  • Application: ELISA ; WB

Handling

  • Format: Liquid
  • Unit size: 100 ug
  • Shipping conditions: Shipping at 4° C

References

  • Rios et al. 2016. Angew Chem Int Ed Engl. 55(10):3387-92. PMID: 26822115.
  • Synthetic Receptors for the High-Affinity Recognition of O-GlcNAc Derivatives.
  • Teo et al. 2010. Nat Chem Biol. 6(5):338-43. PMID: 20305658.
  • Glycopeptide-specific monoclonal antibodies suggest new roles for O-GlcNAc.