Cat. #153779
Anti-Centrobin [6D4F4]
Cat. #: 153779
Sub-type: Primary antibody
Unit size: 100 ug
Availability: 3-5 days
Target: Centrobin, UniProt ID:Q8N137
Class: Monoclonal
Application: IHC ; IF ; IP ; WB
Reactivity: Human
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Ciaran Morrison
Institute: National University of Ireland, Galway; Centre For Chromosome Biology
Tool Details
*FOR RESEARCH USE ONLY
- Name: Anti-Centrobin [6D4F4]
- Alternate name: Centrosomal BRCA2-interacting protein, LYST-interacting protein 8
- Clone: [6D4F4]
- Tool sub type: Primary antibody
- Class: Monoclonal
- Conjugation: Unconjugated
- Molecular weight: 100 kDa (runs at c. 110 kDa on WB)
- Reactivity: Human
- Host: Mouse
- Application: IHC ; IF ; IP ; WB
- Description: Centrobin is a centriole-associated protein that asymmetrically localises to the daughter centriole, and is required for centriole duplication and cytokinesis.
- Immunogen: Recombinant human centrobin amino acids 113-361 (bacterially expressed from pGEX4T as a GST fusion, then thrombin-cleaved and purified).
- Isotype: IgG1 kappa
- Myeloma used: Sp2/0-Ag14
- Recommended controls: IF and WB: hTERT-RPE1, IF only: Jurkat, U2OS, SHSY5Y, DT40 (chicken)
Target Details
- Target: Centrobin, UniProt ID:Q8N137
- Molecular weight: 100 kDa (runs at c. 110 kDa on WB)
- Tissue cell line specificity: IF and WB: hTERT-RPE1, IF only: Jurkat, U2OS, SHSY5Y, DT40 (chicken)
- Target background: Centrobin is a centriole-associated protein that asymmetrically localises to the daughter centriole, and is required for centriole duplication and cytokinesis.
Applications
- Application: IHC ; IF ; IP ; WB
Handling
- Format: Liquid
- Concentration: 1 mg/ml
- Unit size: 100 ug
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -15° C to -25° C
- Shipping conditions: Shipping at 4° C
References
- Ogungbenro et al. 2018. J Cell Biol. 217(4):1205-1215. PMID: 29440264.
- Centrobin controls primary ciliogenesis in vertebrates.
