Cat. #153688
Anti-Cryptococcus [crp127]
Cat. #: 153688
Unit size: 100 ug
Availability: 3-4 weeks
Target: Cryptococcus
Class: Monoclonal
Application: IF ; WB
Reactivity: Cryptococcus gatti; Cryptococcus neoformans
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Robin May
Institute: University of Birmingham
Tool Details
*FOR RESEARCH USE ONLY
- Name: Anti-Cryptococcus [crp127]
- Alternate name: Cryptococcal capsule, Filobasidiella
- Class: Monoclonal
- Conjugation: Unconjugated
- Reactivity: Cryptococcus gatti; Cryptococcus neoformans
- Host: Mouse
- Application: IF ; WB
- Description: Cryptococcus is a genus of fungus of where the majority of organisms are found living in the soil. Cryptococcal cells are covered in a thin gelatin-like layer of capsular glycoprotein material which serves to help extract nutrients from the surroundings. The capsule from C. neoformans which is the most prominent human and animal pathogen in the genus, is different. Its capsule has a greater composition of glucuronic acid and mannose possessing O-acetyl groups and functions as the major virulence factor contributing to cryptococcal infection and disease. The antibody recognises capsular material on the surface of the pathogenic fungi Cryptococcus gattii and C. neoformans. It does not appear to recognise the capsule on the related species C. laurentii and recognition appears to depend on O-acetylation of the capsular polysaccharide.
- Immunogen: Whole, heat-killed Cryptococcus gattii R265
- Isotype: IgM
Target Details
- Target: Cryptococcus
- Target background: Cryptococcus is a genus of fungus of where the majority of organisms are found living in the soil. Cryptococcal cells are covered in a thin gelatin-like layer of capsular glycoprotein material which serves to help extract nutrients from the surroundings. The capsule from C. neoformans which is the most prominent human and animal pathogen in the genus, is different. Its capsule has a greater composition of glucuronic acid and mannose possessing O-acetyl groups and functions as the major virulence factor contributing to cryptococcal infection and disease. The antibody recognises capsular material on the surface of the pathogenic fungi Cryptococcus gattii and C. neoformans. It does not appear to recognise the capsule on the related species C. laurentii and recognition appears to depend on O-acetylation of the capsular polysaccharide.
Applications
- Application: IF ; WB
Handling
- Format: Liquid
- Concentration: 0.9-1.1mg/ml
- Unit size: 100 ug
- Storage buffer: PBS with 0.02% azide
- Storage conditions: Store at 4° C, **DO NOT FREEZE**. Stable for one year from the date of shipment. Non-hazardous. No MSDS required
- Shipping conditions: Shipping at 4° C
