#153649

Anti-Proteolipid protein [PLPC1]

Cat. #153649

Anti-Proteolipid protein [PLPC1]

Cat. #: 153649

Sub-type: Primary antibody

Unit size: 100 ug

Availability: 10-12 weeks

Target: Myelin Proteolipid protein

Class: Monoclonal

Application: FACS ; FACS ; IHC ; IF ; WB

Reactivity: Human ; Tenerife lizard (Gallotia galloti)

Host: Mouse

£300.00

This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.

Contributor

Institute: BioServ UK Ltd

Tool Details
Target Details
Applications
Handling
References

Tool Details

*FOR RESEARCH USE ONLY

  • Name: Anti-Proteolipid protein [PLPC1]
  • Alternate name: Myelin proteolipid protein, PLP, Lipophilin, PLP1
  • Clone: PLPC1
  • Tool sub type: Primary antibody
  • Class: Monoclonal
  • Purpose: Marker
  • Conjugation: Unconjugated
  • Molecular weight: 23-25 kDa
  • Strain: Balb/c
  • Reactivity: Human ; Tenerife lizard (Gallotia galloti)
  • Host: Mouse
  • Application: FACS ; FACS ; IHC ; IF ; WB
  • Description: Proteolipid protein (PLP) is the major myelin protein of the CNS and plays an important role in the formation and maintenance of myelin. Mutations in PLP gene can lead to dysmyelinating diseases. Clone PLPC1 is used in the detection of PLP by various analysis methods.
  • Immunogen: Synthetic peptide GRGTKF that recognizes the C terminal region of myelin proteolipid protein
  • Isotype: IgG2a
  • Myeloma used: Sp2/0-Ag14
  • Recommended controls: Brain tissue

Target Details

  • Target: Myelin Proteolipid protein
  • Molecular weight: 23-25 kDa
  • Tissue cell line specificity: Mouse
  • Target background: Proteolipid protein (PLP) is the major myelin protein of the CNS and plays an important role in the formation and maintenance of myelin. Mutations in PLP gene can lead to dysmyelinating diseases. Clone PLPC1 is used in the detection of PLP by various analysis methods.

Applications

  • Application: FACS ; FACS ; IHC ; IF ; WB

Handling

  • Format: Liquid
  • Unit size: 100 ug
  • Shipping conditions: Shipping at 4° C

References

  • Maccarrone et al. 2017. J Chromatogr B Analyt Technol Biomed Life Sci. 1047:131-140. PMID: 27461358.
  • Cerina et al. 2017. Brain Behav Immun. 59:103-117. PMID: 27569659.
  • The quality of cortical network function recovery depends on localization and degree of axonal demyelination.
  • Chuang et al. 2016. Acta Neuropathol Commun. 4(1):68. PMID: 27400748.
  • LRP1 expression in microglia is protective during CNS autoimmunity.
  • MALDI imaging mass spectrometry analysis-A new approach for protein map...