Cat. #153451
Anti-IFN-Gammarel [VAB4P2B4*E8]
Cat. #: 153451
Unit size: 100 ug
Availability: 10-12 weeks
Target: Anti-IFN-ÄÂ?rel
Class: Monoclonal
Application: ELISA ; IHC ; WB
Reactivity: Salmon ; Brown Trout
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Ayham Alnabulsi
Institute: Vertebrate Antibodies Limited
Tool Details
*FOR RESEARCH USE ONLY
- Name: Anti-IFN-Gammarel [VAB4P2B4*E8]
- Alternate name: IFG antibody, IFI antibody, IFN gamma antibody, IFN immune antibody, IFN-gamma antibody, IFNG antibody, Immune interferon antibody, Interferon gamma antibody
- Clone: VAB4P2B4*E8
- Class: Monoclonal
- Conjugation: Unconjugated
- Molecular weight: 22 kDa
- Strain: Balb/c
- Reactivity: Salmon ; Brown Trout
- Host: Mouse
- Application: ELISA ; IHC ; WB
- Description: Interferons (IFNs) were originally identified as proteins that induce an antiviral state in cells, but they also have important regulatory functions in the immune system. Type I IFN (predominantly IFN-ÄÂ? and IFN-ÄÂ?) and type II IFN (IFN-ÄÂ?) play critical roles in innate and adaptive immune response against viral infection in mammals. Unlike mammals fish have two type II interferons, IFN-ÄÂ? and IFN-ÄÂ?-related (IFN-ÄÂ?rel). IFN-ÄÂ? and IFN-ÄÂ?rel have recently been shown to play a role in protecting particular species of fish against infection by pathogens such as infectious pancreatic necrosis virus (IPNV) and salmonid alphavirus 3 (SAV3). VAB4P2B4*E8 can be used to study IFN-ÄÂ?rel in Atlantic salmon (Salmo salar) and Brown trout (Salmo trutta).
- Immunogen: ovalbumin-conjugated synthetic peptide-DLKRSYYQDR; peptide immunogen is 90% identical to rainbow trout (Oncorhynchus mykiss)
- Isotype: IgG
- Myeloma used: P3X63Ag8.653
- Recommended controls: Western Blot-IFN-ÄÂ?rel recombinant; IHC- Formalin-fixed, paraffin-embedded fish head kidney and spleen
Target Details
- Target: Anti-IFN-ÄÂ?rel
- Molecular weight: 22 kDa
- Target background: Interferons (IFNs) were originally identified as proteins that induce an antiviral state in cells, but they also have important regulatory functions in the immune system. Type I IFN (predominantly IFN-ÄÂ? and IFN-ÄÂ?) and type II IFN (IFN-ÄÂ?) play critical roles in innate and adaptive immune response against viral infection in mammals. Unlike mammals fish have two type II interferons, IFN-ÄÂ? and IFN-ÄÂ?-related (IFN-ÄÂ?rel). IFN-ÄÂ? and IFN-ÄÂ?rel have recently been shown to play a role in protecting particular species of fish against infection by pathogens such as infectious pancreatic necrosis virus (IPNV) and salmonid alphavirus 3 (SAV3). VAB4P2B4*E8 can be used to study IFN-ÄÂ?rel in Atlantic salmon (Salmo salar) and Brown trout (Salmo trutta).
Applications
- Application: ELISA ; IHC ; WB
- Application notes: Recommended Usage Conditions: ELISA- neat, Western Blot- neat, IHC- 1/3, antigen retrieval: microwave 20 min @ 800W in 10 mM citrate buffer, pH 6.0
Handling
- Format: Liquid
- Concentration: 0.9-1.1mg/ml
- Unit size: 100 ug
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -15° C to -25° C
- Shipping conditions: Shipping at 4° C
