#153378

Anti-CEACAM1 (CD66a) [11-1H]

Cat. #153378

Anti-CEACAM1 (CD66a) [11-1H]

Cat. #: 153378

Sub-type: Primary antibody

Unit size: 100 ug

Availability: 1-2 weeks

Target: CEACAM1

Class: Monoclonal

Application: ELISA ; FACS ; IHC ; IF ; IP ; WB

Reactivity: Rat

Host: Mouse

£300.00

This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.

Contributor

Inventor: Bernhard B. Singer

Institute: LeukoCom

Tool Details
Target Details
Applications
Handling
References

Tool Details

*FOR RESEARCH USE ONLY

  • Name: Anti-CEACAM1 (CD66a) [11-1H]
  • Alternate name: CD66, BGP 1, BGP, CD66a, Carcinoembryonic Antigen Related Cell Adhesion Molecule 1; CD66a Antigen; BGP1; BGP; Biliary Glycoprotein 1; Antigen CD66
  • Clone: [11-1H]
  • Tool sub type: Primary antibody
  • Class: Monoclonal
  • Conjugation: Unconjugated
  • Strain: Balb/c
  • Reactivity: Rat
  • Host: Mouse
  • Application: ELISA ; FACS ; IHC ; IF ; IP ; WB
  • Description: Carcinoembryonic antigen related cell adhesion molecules (CEACAM) (CD66a) belong to the immunoglobulin superfamily. They are highly glycosylated proteins with the typical N-terminal variable Ig-like domain followed by 0-6 constant Ig-like domains. A hydrophobic transmembrane domain with a cytoplasmic tail anchors CEACAM1 to the cell membrane. CEACAM1 is known as an epithelial tumour suppressor and an angiogenic growth factor.
  • Immunogen: Recombinant soluble rat CEACAM1-Fc produced in HEK293 cells
  • Isotype: IgG1 kappa
  • Myeloma used: NS1/0
  • Recommended controls: lysate from rat bladder cell line endogenously expressing ratCEACAM1

Target Details

  • Target: CEACAM1
  • Tissue cell line specificity: lysate from rat bladder cell line endogenously expressing ratCEACAM1
  • Target background: Carcinoembryonic antigen related cell adhesion molecules (CEACAM) (CD66a) belong to the immunoglobulin superfamily. They are highly glycosylated proteins with the typical N-terminal variable Ig-like domain followed by 0-6 constant Ig-like domains. A hydrophobic transmembrane domain with a cytoplasmic tail anchors CEACAM1 to the cell membrane. CEACAM1 is known as an epithelial tumour suppressor and an angiogenic growth factor.

Applications

  • Application: ELISA ; FACS ; IHC ; IF ; IP ; WB

Handling

  • Format: Liquid
  • Concentration: 1 mg/ml
  • Unit size: 100 ug
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -15° C to -25° C
  • Shipping conditions: Shipping at 4° C

References

  • Singer et al. 2005. Eur J Immunol. 35(6):1949-59. PMID: 15909305.
  • CEACAM1 (CD66a) mediates delay of spontaneous and Fas ligand-induced apoptosis in granulocytes.
  • Singer et al. 2000. Cancer Res. 60(5):1236-44. PMID: 10728682.
  • The tumor growth-inhibiting cell adhesion molecule CEACAM1 (C-CAM) is differently expressed in proliferating and quiescent epithelial cells and regulates cell proliferation.