#153343

Anti-ELOVL5 [Z88]

Cat. #153343

Anti-ELOVL5 [Z88]

Cat. #: 153343

Sub-type: Primary antibody

Unit size: 100 ug

Availability: 3-4 weeks

Target: ELOVL Fatty Acid Elongase 5

Class: Monoclonal

Application: ELISA ; IHC ; WB

Reactivity: Human

Host: Mouse

£300.00

This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.

Contributor

Inventor: Ayham Alnabulsi

Institute: Vertebrate Antibodies Limited

Tool Details
Target Details
Applications
Handling
References

Tool Details

*FOR RESEARCH USE ONLY

  • Name: Anti-ELOVL5 [Z88]
  • Alternate name: Elongation of very long chain fatty acids protein 5; ELOVL5; 3-keto acyl-CoA synthase ELOVL5; ELOVL FA elongase 5; Fatty acid elongase 1; Very long chain 3-ketoacyl-CoA synthase 5
  • Clone: Z88
  • Tool sub type: Primary antibody
  • Class: Monoclonal
  • Conjugation: Unconjugated
  • Strain: Balb/c
  • Reactivity: Human
  • Host: Mouse
  • Application: ELISA ; IHC ; WB
  • Description: This protein is involved in the elongation of long-chain polyunsaturated fatty acids functioning as a condensing enzyme that acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C18:3(n-6) acyl-CoA. It may also participate in the production of monounsaturated and of polyunsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators. It is highly expressed in the adrenal gland and testis, and encodes a multi-pass membrane protein that is localized in the endoplasmic reticulum.
  • Immunogen: Peptide Sequence NNVKPRKLR (peptide immunogen is identical in primates)
  • Isotype: IgG
  • Myeloma used: P3X63Ag8.653
  • Recommended controls: Western Blot: Jurkat cell lysates. IHC: formalin-fixed, paraffin-embedded multi tumour tissue microarray.

Target Details

  • Target: ELOVL Fatty Acid Elongase 5
  • Tissue cell line specificity: Western Blot: Jurkat cell lysates. IHC: formalin-fixed, paraffin-embedded multi tumour tissue microarray.
  • Target background: This protein is involved in the elongation of long-chain polyunsaturated fatty acids functioning as a condensing enzyme that acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C18:3(n-6) acyl-CoA. It may also participate in the production of monounsaturated and of polyunsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators. It is highly expressed in the adrenal gland and testis, and encodes a multi-pass membrane protein that is localized in the endoplasmic reticulum.

Applications

  • Application: ELISA ; IHC ; WB

Handling

  • Format: Liquid
  • Concentration: 0.9-1.1 mg/ml
  • Unit size: 100 ug
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -15° C to -25° C
  • Shipping conditions: Shipping at 4° C

References

  • The expression of brown fat-associated proteins in colorectal cancer and the relationship of uncoupling protein 1 with prognosis.
  • The expression of brown fat associated proteins in colorectal cancer and the relationship of uncoupling protein 1 with prognosis. Alnabulsi et al. 2019. Int J Cancer. :. PMID: 30737786.