Cat. #153260
Anti-S100A8 & S100A9 [5.5] rAb
Cat. #: 153260
Sub-type: Primary antibody
Unit size: 100 ug
Availability: 10-12 weeks
Target: S100A8 (MRP-8) & S100A9 (MRP-14)
Class: Recombinant
Application: ELISA ; FACS ; IHC ; IP ; WB
Reactivity: Human
Host: Mouse
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Nancy Hogg
Institute: Absolute Antibody ; Cancer Research UK, London Research Institute: Lincoln's Inn Fields
Tool Details
*FOR RESEARCH USE ONLY
- Name: Anti-S100A8 & S100A9 [5.5] rAb
- Clone: 5.5
- Tool sub type: Primary antibody
- Class: Recombinant
- Conjugation: Unconjugated
- Reactivity: Human
- Host: Mouse
- Application: ELISA ; FACS ; IHC ; IP ; WB
- Description: S100A8 (MRP-8) and S100A9 (MRP-14) are cytosolic calcium-binding proteins of 8kDa and 14kDa that form a heterodimer. S100A8 and S100A9 are expressed in secretory and inflamed keratinocytes, peripheral blood monocytes, neutrophils and has been described in platelets, dendritic cells and some T cell types. Expression is lost on tissue maturation of monocytes to macrophages. S100A9 may be associated with monocyte and neutrophil activation and the accumulation of these cells in inflammatory sites.
- Immunogen: Acute monocytic leukaemia cells.
- Isotype: IgG1
Target Details
- Target: S100A8 (MRP-8) & S100A9 (MRP-14)
- Target background: S100A8 (MRP-8) and S100A9 (MRP-14) are cytosolic calcium-binding proteins of 8kDa and 14kDa that form a heterodimer. S100A8 and S100A9 are expressed in secretory and inflamed keratinocytes, peripheral blood monocytes, neutrophils and has been described in platelets, dendritic cells and some T cell types. Expression is lost on tissue maturation of monocytes to macrophages. S100A9 may be associated with monocyte and neutrophil activation and the accumulation of these cells in inflammatory sites.
Applications
- Application: ELISA ; FACS ; IHC ; IP ; WB
Handling
- Format: Liquid
- Concentration: 1 mg/ml
- Unit size: 100 ug
- Storage buffer: PBS
- Shipping conditions: Shipping at 4° C
References
- Original hybridoma first published in: Hogg et al. 1989. Eur J Immunol. 19(6):1053-61. PMID: 2666142.
