Cat. #153198
Anti-CHIKV [3E7b] mAb
Cat. #: 153198
Unit size: 100 ug
Availability: 3-4 weeks
Target: N218 epitope on E2 protein of CHIKV
Class: Monoclonal
Application: ELISA ; IHC ; Fn ; WB
Reactivity: Virus
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Institute: A*STAR Accelerate Technologies Pte Ltd
Primary Citation: Lam et al. 2015. MAbs. 7(6):1178-1194. PMID: 26305993.
Tool Details
*FOR RESEARCH USE ONLY
- Name: Anti-CHIKV [3E7b] mAb
- Alternate name: Chikungunya virus; Chikungunya virus antibody
- Clone: 3E7b
- Class: Monoclonal
- Conjugation: Unconjugated
- Reactivity: Virus
- Host: Mouse
- Application: ELISA ; IHC ; Fn ; WB
- Description: Anti-CHIKV [3E7b] binds strongly to the native CHIKV surface. This monoclonal antibody is also capable of detecting infection of cells. Chikungunya virus (CHIKV) is an alphavirus known to cause severe polyarthritis and polyarthralgia. CHIKV is transmitted to humans by mosquito vectors, primarily Aedes aegypti and Aedes albopictus. 3E7b potently neutralises CHIKV replication. Additionally, Anti-CHIKV [3E7b] protected mice from CHIKV disease when administered prior to CHIKV infection.
- Immunogen: Live chikungunya virus
- Immunogen uniprot id: Q8JUX5
- Isotype: IgM
- Myeloma used: Sp2/0-Ag14
- Recommended controls: Infected BHK cells
Target Details
- Target: N218 epitope on E2 protein of CHIKV
- Target background: Chikungunya virus (CHIKV) is an alphavirus which causes febrile illness with severe polyarthralgia, known to be transmitted to humans by mosquito vectors, primarily Aedes aegypti and A. albopictus. Symptoms include high fever, asthenia, chills, headache, diarrhoea, vomiting and rash. Since the re-emergence of CHIKV in La Reunion, epidemic outbreaks of CHIKV infection have been reported globally and CHIKV is now considered endemic in 34 countries across Europe, Australia, Asia and Africa.
Applications
- Application: ELISA ; IHC ; Fn ; WB
Handling
- Format: Liquid
- Concentration: 1 mg/ml
- Unit size: 100 ug
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -15° C to -25° C
- Shipping conditions: Shipping at 4° C
Related Tools
- Related tools: Anti-CHIKV [8A2c] ; Anti-CHIKV [6A11] ; Anti-CHIKV [11E7]
References
- Lam et al. 2015. MAbs. 7(6):1178-1194. PMID: 26305993.
