Cat. #152843
BICR 18 Cell Line
Cat. #: 152843
Unit size: 1x10^6 cells / vial
Organism: Human
Tissue: Larynx
Disease: Cancer
Model: Tumour line
£575.00
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Contributor
Inventor: Eric Kenneth Parkinson
Institute: Cancer Research UK, Glasgow: The Beatson Institute
Tool Details
*FOR RESEARCH USE ONLY
- Name: BICR 18 Cell Line
- Organism: Human
- Tissue: Larynx
- Disease: Cancer
- Growth properties: Adherent
- Model: Tumour line
- Conditional: Yes
- Description: Adherent keratinocyte cell line derived from a lymph node metastasis squamous cell carcinoma (SSC) of the larynx. Keratin and involucrin markers present. Known mutations: p53, p16 and p14ARF. Cells are tumourigenic in athymic mice. By short tandem repeat (STR)-PCR analysis the Y chromosome could not be detected in this cell line. It is a known phenomenon that SSC cell lines can lose their Y chromosome.
- Additional notes: STR-PCR Data: Amelogenin: X CSF1PO: 11,12 D13S317: 8,13 D16S539: 12,14 D5S818: 12 D7S820: 9 THO1: 7 TPOX: 9,12 vWA: 17,20
- Cellosaurus id: CVCL_2309
Applications
- Application notes: STR-PCR Data: Amelogenin: X CSF1PO: 11,12 D13S317: 8,13 D16S539: 12,14 D5S818: 12 D7S820: 9 THO1: 7 TPOX: 9,12 vWA: 17,20
Handling
- Format: Frozen
- Growth medium: DMEM + 2mM Glutamine + 10% Foetal Bovine Serum (FBS) + 0.4 micrograms/ml Hydrocortisone.
- Unit size: 1x10^6 cells / vial
- Shipping conditions: Dry ice
Related Tools
- Related tools: BICR 10 Cell Line ; BICR 16 Cell Line ; BICR 3 Cell Line ; BICR 56 Cell Line ; BICR 6 Cell Line ; BICR 78 Cell Line ; BICR 22 Cell Line ; BICR 31 Cell Line ; BICR 82 Cell Line
References
- Edington et al. 1995. Mol Carcinog. 13(4):254-65. PMID: 7646764.
- Cellular immortality: a late event in the progression of human squamous cell carcinoma of the head and neck associated with p53 alteration and a high frequency of allele loss.