![Immunohistochemistry was performed on formalin-fixed; paraffin-embedded breast cancer tissue sections using anti-TMEM2L [V98P4E1*B7] antibody. Strong cytoplasmic and nuclear staining were detected.](https://cancertools.org/wp-content/uploads/f08ea08e-8d19-470e-be62-a14e60e1dc95.jpg "f08ea08e-8d19-470e-be62-a14e60e1dc95.jpg")
Cat. #152769
Anti-TMEM2L [V98P4E1*B7]
Cat. #: 152769
Sub-type: Primary antibody
Unit size: 100 ug
Availability: 3-5 days
Target: Cell migration-inducing and hyaluronan-binding protein
Class: Monoclonal
Application: ELISA ; IHC
Reactivity: Human
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Ayham Alnabulsi
Institute: Vertebrate Antibodies Limited
Tool Details
*FOR RESEARCH USE ONLY
- Name: Anti-TMEM2L [V98P4E1*B7]
- Alternate name: CEMIP, KIAA1199, CCSP1, IR2155535, Protein KIAA1199, TMEM2L
- Clone: V98P4E1*B7
- Tool sub type: Primary antibody
- Class: Monoclonal
- Conjugation: Unconjugated
- Molecular weight: 153 kDa (isoform 1), 110 kDa (isoform 2)
- Strain: Balb/c
- Reactivity: Human
- Host: Mouse
- Application: ELISA ; IHC
- Description: TMEM2L mediates depolymerization of hyaluronic acid (HA) via the cell membrane-associated clathrin-coated pit endocytic pathway. Binds to hyaluronic acid. Hydrolyzes high molecular weight hyaluronic acid to produce an intermediate-sized product, a process that may occur through rapid vesicle endocytosis and recycling without intracytoplasmic accumulation or digestion in lysosomes. Involved in hyaluronan catabolism in the dermis of the skin and arthritic synovium. Positively regulates epitheli...
- Immunogen: Peptide Sequence VTLDTEDHKA peptide immunogen is identical in horse (Equus caballus), 90% identical in mouse (Mus musculus) and rat (Rattus norvegicus)
- Isotype: IgG1 kappa
- Myeloma used: P3X63Ag8.653
Target Details
- Target: Cell migration-inducing and hyaluronan-binding protein
- Molecular weight: 153 kDa (isoform 1), 110 kDa (isoform 2)
- Target background: TMEM2L mediates depolymerization of hyaluronic acid (HA) via the cell membrane-associated clathrin-coated pit endocytic pathway. Binds to hyaluronic acid. Hydrolyzes high molecular weight hyaluronic acid to produce an intermediate-sized product, a process that may occur through rapid vesicle endocytosis and recycling without intracytoplasmic accumulation or digestion in lysosomes. Involved in hyaluronan catabolism in the dermis of the skin and arthritic synovium. Positively regulates epitheli...
Applications
- Application: ELISA ; IHC
Handling
- Format: Liquid
- Concentration: 1 mg/ml
- Unit size: 100 ug
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -15° C to -25° C
- Shipping conditions: Shipping at 4° C
