Cat. #152667
Anti-VTN2 [1A5]
Cat. #: 152667
Unit size: 100 ug
Availability: 10-12 weeks
Target: Splice variant of Zebrafish IKKg protein (154 amino acids)
Class: Monoclonal
Application: IF ; WB
Reactivity: Human ; Zebrafish
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Institute: A*STAR Accelerate Technologies Pte Ltd
Tool Details
*FOR RESEARCH USE ONLY
- Name: Anti-VTN2 [1A5]
- Clone: 1A5
- Class: Monoclonal
- Conjugation: Unconjugated
- Reactivity: Human ; Zebrafish
- Host: Mouse
- Application: IF ; WB
- Description: NF-ÄÂ?B (nuclear factor kappaB) is a transcription factor that activates numerous target genes important in mediating innate and adaptive immunity in mammals. Activation by external stimuli such as TNF leads to the activation of kinases (IKK1 and IKK2) that phosphorylate inhibitory proteins I-ÄÂ?B and their subsequent degradation. IKK1 and IKK2 form the catalytic subunits of a complex which includes IKKÄÂ?, the regulatory component (also known as NEMO). Mutations in NEMO are the cause of the human disorders incontinentia pigmenti and ectodermal dysplasia (ED-AID).
- Immunogen: GST/His-tagged splice variant of Zebrafish IKK? protein of 154 amino acids fusion protein
- Isotype: IgG1
- Myeloma used: Sp2/0-Ag14
- Recommended controls: Zebrafish embryos, HEK293 cells
Target Details
- Target: Splice variant of Zebrafish IKKg protein (154 amino acids)
- Target background: NF-ÄÂ?B (nuclear factor kappaB) is a transcription factor that activates numerous target genes important in mediating innate and adaptive immunity in mammals. Activation by external stimuli such as TNF leads to the activation of kinases (IKK1 and IKK2) that phosphorylate inhibitory proteins I-ÄÂ?B and their subsequent degradation. IKK1 and IKK2 form the catalytic subunits of a complex which includes IKKÄÂ?, the regulatory component (also known as NEMO). Mutations in NEMO are the cause of the human disorders incontinentia pigmenti and ectodermal dysplasia (ED-AID).
Applications
- Application: IF ; WB
Handling
- Format: Liquid
- Concentration: 0.9-1.1mg/ml
- Unit size: 100 ug
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -15° C to -25° C
- Shipping conditions: Shipping at 4° C
