Cat. #151885
Anti-Alkaline phosphatase [AP1B9]
Cat. #: 151885
Sub-type: Primary antibody
Unit size: 100 ug
Availability: 1-2 weeks
Target: Calf alkaline phosphatase
Class: Monoclonal
Application: IHC
Reactivity: Bovine ; Human
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Peter Beverley
Institute: Cancer Research UK, London Research Institute: Lincoln's Inn Fields
Tool Details
*FOR RESEARCH USE ONLY
- Name: Anti-Alkaline phosphatase [AP1B9]
- Clone: AP1B9
- Tool sub type: Primary antibody
- Class: Monoclonal
- Conjugation: Unconjugated
- Strain: Balb/c
- Reactivity: Bovine ; Human
- Host: Mouse
- Application: IHC
- Description: Monoclonal antibody which can aid detection of ovarian and testicular cancers.
- Immunogen: Calf Alkaline phosphatase
- Immunogen uniprot id: P09923
- Isotype: IgG1
- Myeloma used: P3/NS1/1-Ag4.1
- Recommended controls: Human tonsil
Target Details
- Target: Calf alkaline phosphatase
- Tissue cell line specificity: Human tonsil
- Target background: Alkaline phosphatases are phosphodiesterases which remove phosphate groups from the 5' end of DNA, RNA and proteins at high pH. The placental-specific isozyme of Alkaline Phosphatase (PLAP) is found in trophoblast cells of normal human mature placenta, seminomas of testis and ovarian carcinomas. Detection of alkaline phosphatase in serum is a marker for ovarian and testicular cancer.
Applications
- Application: IHC
Handling
- Format: Liquid
- Concentration: 1 mg/ml
- Unit size: 100 ug
- Storage buffer: PBS with 0.02% azide
- Storage conditions: Store at -20° C frozen. Avoid repeated freeze / thaw cycles
- Shipping conditions: Shipping at 4° C
References
- Hoene et al. 2020. J Biomed Mater Res A. 108(4):871-881. PMID: 31846170.
- Lucke et al. 2018. J Biomed Mater Res A. 106(10):2726-2734. PMID: 30051967.
- Lucke et al. 2015. Biomed Res Int. 2015:938059. PMID: 25648958.
- Erlach et al. 2002. J Virol. 76(6):2857-70. PMID: 11861853.
- Tumor control in a model of bone marrow transplantation and acute liver-infiltrating B-cell lymphoma: an unpredicted novel function of cytomegalovirus.
