Cat. #151875
Anti-POT1 [M1-P1H5]
Cat. #: 151875
Sub-type: Primary antibody
Unit size: 100 ug
Availability: 1-2 weeks
Target: Protection of telomeres 1 (POT1)
Class: Monoclonal
Application: ELISA ; IF ; WB
Reactivity: Human
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Ayham Alnabulsi
Institute: Vertebrate Antibodies Limited
Tool Details
*FOR RESEARCH USE ONLY
- Name: Anti-POT1 [M1-P1H5]
- Clone: M1-P1H5
- Tool sub type: Primary antibody
- Class: Monoclonal
- Conjugation: Unconjugated
- Strain: Balb/c
- Reactivity: Human
- Host: Mouse
- Application: ELISA ; IF ; WB
- Description: POT1 (protection of telomeres 1) is part of the telomerase ribonucleotide (RNP) complex, which stabilises chromosomes by controlling telomere elongation. POT1 is a component of the double-stranded telomeric DNA-binding TRF1 complex which cis-inhibits telomerase. POT1 localization on telomeres diminishes in the absence of single-stranded DNA.
- Immunogen: Peptide sequence - IPASEVLMDD
- Isotype: IgG1 kappa
- Recommended controls: ELISA- Peptide immunogenWestern Blot- Hela cell extract (nuclear fraction)IF- Hela Cells
Target Details
- Target: Protection of telomeres 1 (POT1)
- Tissue cell line specificity: ELISA- Peptide immunogenWestern Blot- Hela cell extract (nuclear fraction)IF- Hela Cells
- Target background: POT1 (protection of telomeres 1) is part of the telomerase ribonucleotide (RNP) complex, which stabilises chromosomes by controlling telomere elongation. POT1 is a component of the double-stranded telomeric DNA-binding TRF1 complex which cis-inhibits telomerase. POT1 localization on telomeres diminishes in the absence of single-stranded DNA.
Applications
- Application: ELISA ; IF ; WB
Handling
- Format: Liquid
- Concentration: 1 mg/ml
- Unit size: 100 ug
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -15° C to -25° C
- Shipping conditions: Shipping at 4° C
